GBA, Gaucher Disease, and Parkinson's Disease: From Genetic to Clinic to New Therapeutic Approaches
GM Riboldi, AB Di Fonzo - Cells, 2019 - mdpi.com
Parkinson's disease (PD) is the second most common degenerative disorder. Although the
disease was described more than 200 years ago, its pathogenetic mechanisms have not yet …
disease was described more than 200 years ago, its pathogenetic mechanisms have not yet …
The risk of neurodegeneration in REM sleep behavior disorder: a systematic review and meta-analysis of longitudinal studies
Several studies report an association between REM Sleep Behavior Disorder (RBD) and
neurodegenerative diseases, in particular synucleinopathies. Interestingly, the onset of RBD …
neurodegenerative diseases, in particular synucleinopathies. Interestingly, the onset of RBD …
Sleep, cognition and dementia
VR Porter, WG Buxton, AY Avidan - Current psychiatry reports, 2015 - Springer
The older patient population is growing rapidly around the world and in the USA. Almost half
of seniors over age 65 who live at home are dissatisfied with their sleep, and nearly two …
of seniors over age 65 who live at home are dissatisfied with their sleep, and nearly two …
Is sleep disruption a risk factor for Alzheimer's disease?
Sleep disturbances are routinely encountered in Alzheimer's disease (AD) and affect about
25–40% of patients in the mild-to-moderate stages of the disease. In many, sleep pathology …
25–40% of patients in the mild-to-moderate stages of the disease. In many, sleep pathology …
Associations of sleep disorders with cerebrospinal fluid α-synuclein in prodromal and early Parkinson's disease
XT Wang, H Yu, FT Liu, C Zhang, YH Ma, J Wang… - Journal of …, 2022 - Springer
Objectives Our aim is to investigate the associations of sleep disorders with cerebrospinal
fluid (CSF) α-synuclein (α-syn) in healthy controls (HCs), and patients with prodromal and …
fluid (CSF) α-synuclein (α-syn) in healthy controls (HCs), and patients with prodromal and …
Longitudinal alterations of alpha-synuclein, amyloid beta, total, and phosphorylated tau in cerebrospinal fluid and correlations between their changes in Parkinson's …
Background: Parkinson's disease (PD) is characterized by proteinopathies and these
proteinopathies seem to interact synergistically and lead to protein aggregations and …
proteinopathies seem to interact synergistically and lead to protein aggregations and …
Defining optimal exercises for efficient detection of Parkinson's disease using machine learning and wearable sensors
A Talitckii, A Anikina, E Kovalenko… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
Our society exhibits a worldwide trait of a quickly growing cohort of patients with
neurodegenerative diseases, such as Parkinson's disease (PD). According to the analysts …
neurodegenerative diseases, such as Parkinson's disease (PD). According to the analysts …
Behavioural and cognitive‐behavioural treatments of parasomnias
Parasomnias are unpleasant or undesirable behaviours or experiences that occur
predominantly during or within close proximity to sleep. Pharmacological treatments of …
predominantly during or within close proximity to sleep. Pharmacological treatments of …
Deep learning framework for neurological diseases diagnosis through near-infrared eye video and time series imaging algorithms
Abstract Internet of Things (IoT) solutions have greatly evolved recently with the application
of Artificial Intelligence (AI). Indeed, AI enriches the IoT with intelligence capabilities. In …
of Artificial Intelligence (AI). Indeed, AI enriches the IoT with intelligence capabilities. In …
REM sleep behavior disorder, autonomic dysfunction and synuclein-related neurodegeneration: where do we stand?
G Chiaro, G Calandra-Buonaura, A Cecere… - Clinical Autonomic …, 2018 - Springer
Introduction From newfound parasomnia to a marker of future synucleinopathy, since its first
description in 1986, REM sleep behavior disorder (RBD) has been systematically tackled …
description in 1986, REM sleep behavior disorder (RBD) has been systematically tackled …