Diabetes and tuberculosis

BI Restrepo - Understanding the host immune response against …, 2018 - Springer
The worldwide increase in the prevalence of diabetes has been most notable in TB-endemic
countries and has led to the re-emerging importance of the association between these two …

Influence of diabetes mellitus on immunity to human tuberculosis

P Kumar Nathella, S Babu - Immunology, 2017 - Wiley Online Library
Type 2 diabetes mellitus (DM) is a major risk factor for the development of active pulmonary
tuberculosis (TB), with development of DM pandemic in countries where TB is also endemic …

Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human Diseases

Q Chai, Y Zhang, CH Liu - Frontiers in cellular and infection …, 2018 - frontiersin.org
Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely
successful pathogen that adapts to survive within the host. During the latency phase of …

Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus

K Ronacher, SA Joosten, R van Crevel… - Immunological …, 2015 - Wiley Online Library
The spread of human immunodeficiency virus (HIV) infection within Africa led to marked
increases in numbers of cases of tuberculosis (TB), and although the epidemic peaked in …

Diabetes mellitus and increased tuberculosis susceptibility: the role of short‐chain fatty acids

E Lachmandas, CNAM van den Heuvel… - Journal of diabetes …, 2016 - Wiley Online Library
Type 2 diabetes mellitus confers a threefold increased risk for tuberculosis, but the
underlying immunological mechanisms are still largely unknown. Possible mediators of this …

[HTML][HTML] Tuberculosis and diabetes mellitus: Relating immune impact of co-morbidity with challenges in disease management in high burden countries

U Abbas, KI Masood, A Khan, M Irfan… - Journal of clinical …, 2022 - Elsevier
Mycobacterium tuberculosis (MTB) is the causative agent of TB. TB incidence is high in
many low resource settings where limited health systems make it difficult for screening of co …

IL-22 as a target for therapeutic intervention: current knowledge on its role in various diseases

P Seth, S Dubey - Cytokine, 2023 - Elsevier
IL-22 has emerged as a crucial cytokine mediating protective response against pathogens
and tissue regeneration. Dysregulated production of IL-22 has been shown to play a pivotal …

Immunologic, metabolic and genetic impact of diabetes on tuberculosis susceptibility

P Ssekamatte, OJ Sande, R Van Crevel… - Frontiers in …, 2023 - frontiersin.org
Due to the increasing prevalence of diabetes mellitus (DM) globally, the interaction between
DM and major global diseases like tuberculosis (TB) is of great public health significance …

IL-22: an underestimated player in natural resistance to tuberculosis?

K Ronacher, R Sinha, M Cestari - Frontiers in immunology, 2018 - frontiersin.org
Approximately 10% of individuals latently infected with Mycobacterium tuberculosis (Mtb)
develop active tuberculosis (TB) during their lifetime. Although it is well recognized that T …

Associated risk factors for latent tuberculosis infection in subjects with diabetes

G Martínez-Aguilar, CJ Serrano… - Archives of medical …, 2015 - Elsevier
Background and Aims Type 2 diabetes mellitus (DM2) confers a higher risk for active
tuberculosis (TB). However, information on associated risk factors for latent tuberculosis …