Placental model as an important tool to study maternal-fetal interface
BM Gonçalves, JB Graceli, PB da Rocha, HP Tilli… - Reproductive …, 2022 - Elsevier
The placenta is a temporary organ that plays critical roles at the maternal-fetal interface.
Normal development and function of the placenta is dependent on hormonal signaling …
Normal development and function of the placenta is dependent on hormonal signaling …
Bioengineering approaches for placental research
ML Wheeler, ML Oyen - Annals of Biomedical Engineering, 2021 - Springer
Research into the human placenta's complex functioning is complicated by a lack of suitable
physiological in vivo models. Two complementary approaches have emerged recently to …
physiological in vivo models. Two complementary approaches have emerged recently to …
A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta
WM Tun, G Poologasundarampillai… - Journal of The …, 2021 - royalsocietypublishing.org
Multi-scale structural assessment of biological soft tissue is challenging but essential to gain
insight into structure–function relationships of tissue/organ. Using the human placenta as an …
insight into structure–function relationships of tissue/organ. Using the human placenta as an …
Anomalous diffusion of deformable particles in a honeycomb network
Transport of deformable particles in a honeycomb network is studied numerically. It is shown
that the particle deformability has a strong impact on their distribution in the network. For …
that the particle deformability has a strong impact on their distribution in the network. For …
[HTML][HTML] Ex vivo dual perfusion of an isolated human placenta cotyledon: Towards protocol standardization and improved inter-centre comparability
H Schneider, C Albrecht, MS Ahmed, M Broekhuizen… - Placenta, 2022 - Elsevier
Since the full development of the ex vivo dual perfusion model of the human placenta
cotyledon, the technique has provided essential insight into how nutrients, lipids, gases …
cotyledon, the technique has provided essential insight into how nutrients, lipids, gases …
Structure-function relationships in the feto-placental circulation from in silico interpretation of micro-CT vascular structures
M Byrne, R Aughwane, JL James… - Journal of theoretical …, 2021 - Elsevier
A well-functioning placenta is critical for healthy fetal development, as the placenta brings
fetal blood in close contact with nutrient rich maternal blood, enabling exchange of nutrients …
fetal blood in close contact with nutrient rich maternal blood, enabling exchange of nutrients …
Multi-scale modelling of shear stress on the Syncytiotrophoblast: could maternal blood flow impact placental function across gestation?
The placenta is a critical fetal exchange organ, with a complex branching tree-like structure.
Its surface is covered by a single multinucleated cell, the syncytiotrophoblast, which bathes …
Its surface is covered by a single multinucleated cell, the syncytiotrophoblast, which bathes …
Multiscale three-dimensional imaging of the placenta
RM Lewis, JE Pearson-Farr - Placenta, 2020 - Elsevier
Placental function involves multiple different processes which operate at different scales
from centimetres to nanometres. Everything that the placenta does from mediating blood …
from centimetres to nanometres. Everything that the placenta does from mediating blood …
Computational modeling of the interactions between the maternal and fetal circulations in human pregnancy
In pregnancy, fetal growth is supported by its placenta. In turn, the placenta is nourished by
maternal blood, delivered from the uterus, in which the vasculature is dramatically …
maternal blood, delivered from the uterus, in which the vasculature is dramatically …
Transcriptional and epigenomic markers of the arterial-venous and micro/macro-vascular endothelial heterogeneity within the umbilical-placental bed
Umbilical and placental vessels and endothelial cells (EC) are common models to study
placental function and vascular programming. Arterio-venous differences are present in the …
placental function and vascular programming. Arterio-venous differences are present in the …