Breast conservation therapy (BCT) is the procedure of choice for the management of the
early stage breast cancer. However, its utilization has not been maximized because of …

Several randomized controlled trials have demonstrated the benefit of a boost to the tumor
bed (TB) to reduce the risk of ipsilateral breast tumor recurrence. Recent technological …

The goal of Task Group 25 (TG‐25) of the Radiation Therapy Committee of the American
Association of Physicists in Medicine (AAPM) was to provide a methodology and set of …

PURPOSE: We have previously shown that delivering targeted radiotherapy to the tumour
bed intraoperatively is feasible and desirable. In this study, we report on the feasibility …

BACKGROUND AND PURPOSE: To determine the interobserver variability of clinical target
volume delineation of glandular breast tissue and of boost volume in tangential breast …

Purpose: The standard radiotherapy (RT) of breast cancer consists of 50 Gy external beam
RT (EBRT) to the whole breast followed by an electron boost of 10–16 Gy to the tumor bed …

PURPOSE: We hypothesize that surgical clips placed in the biopsy cavity during
lumpectomy can be used as radiographic markers to facilitate image-guided external beam …

Breast-conserving surgery requires supportive radiotherapy to prevent cancer recurrence.
However, the task of localizing the tumor bed to be irradiated is not trivial. The automatic …

Purpose: Patients undergoing breast-conserving surgery were offered boost radiotherapy
with targeted intraoperative radiotherapy (TARGIT) using the Intrabeam system to test the …

PURPOSE: Intraoperative radiotherapy (IORT) during breast-conserving surgery (BCS) has
been recently introduced using different devices. We report the first 5 years of a single …