Functional nucleic acid biosensors utilizing rolling circle amplification

RM Bialy, A Mainguy, Y Li, JD Brennan - Chemical Society Reviews, 2022 - pubs.rsc.org
Functional nucleic acids (FNAs), including DNA aptamers and DNAzymes, are finding
increasing use as molecular recognition elements for point-of-care (POC) assays and …

Recent applications of rolling circle amplification in biosensors and DNA nanotechnology

J Liu, G Xie, S Lv, Q Xiong, H Xu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Isothermal nucleic acid amplification techniques have emerged as an important diagnostic
tool for clinical applications and food safety inspection. Rolling circle amplification (RCA) is …

Electrochemical detection of a few copies of unamplified SARS-CoV-2 nucleic acids by a self-actuated molecular system

D Ji, M Guo, Y Wu, W Liu, S Luo, X Wang… - Journal of the …, 2022 - ACS Publications
The existing electrochemical biosensors lack controllable and intelligent merit to modulate
the sensing process upon external stimulus, leading to challenges in analyzing a few copies …

Biosensing strategies for the electrochemical detection of viruses and viral diseases–A review

LC Brazaca, PL Dos Santos, PR de Oliveira… - Analytica Chimica …, 2021 - Elsevier
Viruses are the causing agents for many relevant diseases, including influenza, Ebola,
HIV/AIDS, and COVID-19. Its rapid replication and high transmissibility can lead to serious …

Internet‐of‐medical‐things integrated point‐of‐care biosensing devices for infectious diseases: Toward better preparedness for futuristic pandemics

A Parihar, S Yadav, MA Sadique… - Bioengineering & …, 2023 - Wiley Online Library
Microbial pathogens have threatened the world due to their pathogenicity and ability to
spread in communities. The conventional laboratory‐based diagnostics of microbes such as …

Point of care sensors for infectious pathogens

M Sharafeldin, JJ Davis - Analytical Chemistry, 2020 - ACS Publications
In the wake of the COVID-19 pandemic, the World Health Organization (WHO) has called for
an urgent global collaboration to develop fast, simple, and accurate tests capable of curbing …

[HTML][HTML] Virus detection: a review of the current and emerging molecular and immunological methods

A Cassedy, A Parle-McDermott… - Frontiers in Molecular …, 2021 - frontiersin.org
Viruses are ubiquitous in the environment. While many impart no deleterious effects on their
hosts, several are major pathogens. This risk of pathogenicity, alongside the fact that many …

Rolling circle amplification in integrated microsystems: An uncut gem toward massively multiplexed pathogen diagnostics and genotyping

RRG Soares, N Madaboosi… - Accounts of Chemical …, 2021 - ACS Publications
Conspectus The development of robust methods allowing the precise detection of specific
nucleic acid sequences is of major societal relevance, paving the way for significant …

[HTML][HTML] DNA/RNA electrochemical biosensing devices a future replacement of PCR methods for a fast epidemic containment

M Santhanam, I Algov, L Alfonta - Sensors, 2020 - mdpi.com
Pandemics require a fast and immediate response to contain potential infectious carriers. In
the recent 2020 Covid-19 worldwide pandemic, authorities all around the world have failed …

Nanosensors for diagnosis of infectious diseases

J Deng, S Zhao, Y Liu, C Liu, J Sun - ACS Applied Bio Materials, 2020 - ACS Publications
Infectious diseases have become a severe global public health problem. Timely and
accurate diagnosis of infected individuals is the key step to control the spread of infectious …