Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Oxidative stress and natural antioxidants: Back and forth in the neurological mechanisms of Alzheimer's Disease

S Mani, R Dubey, IC Lai, MA Babu… - Journal of …, 2023 - journals.sagepub.com
Alzheimer's disease (AD) is characterized by the progressive degeneration of neuronal
cells. With the increase in aged population, there is a prevalence of irreversible …

Antioxidant and neuroprotective effects of carnosine: therapeutic implications in neurodegenerative diseases

C Solana-Manrique, FJ Sanz, G Martínez-Carrión… - Antioxidants, 2022 - mdpi.com
Neurodegenerative diseases (NDs) constitute a global challenge to human health and an
important social and economic burden worldwide, mainly due to their growing prevalence in …

A triterpenoid lupeol as an antioxidant and anti-neuroinflammatory agent: impacts on oxidative stress in Alzheimer's disease

JS Park, IU Rehman, K Choe, R Ahmad, HJ Lee… - Nutrients, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease illustrated by
neuronal dysfunctions, leading to memory weaknesses and personality changes mostly in …

A comprehensive review of summer savory (Satureja hortensis L.): promising ingredient for production of functional foods

A Ejaz, S Waliat, MS Arshad, W Khalid… - Frontiers in …, 2023 - frontiersin.org
This review aims to measure the different aspects of summer savory including biological
activity, medicinal properties, nutritional value, food application, prospective health benefits …

[HTML][HTML] The Interplay of Protein Aggregation, Genetics, and Oxidative Stress in Alzheimer's Disease: Role for Natural Antioxidants and Immunotherapeutics

J Ali, K Choe, JS Park, HY Park, H Kang, TJ Park… - Antioxidants, 2024 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that comprises
amyloid-beta protein (Aβ) as a main component of neuritic plaques. Its deposition is …

Antibody-mediated clearance of brain amyloid-β: mechanisms of action, effects of natural and monoclonal anti-Aβ antibodies, and downstream effects

DA Loeffler - Journal of Alzheimer's disease reports, 2023 - content.iospress.com
Immunotherapeutic efforts to slow the clinical progression of Alzheimer's disease (AD) by
lowering brain amyloid-β (Aβ) have included Aβ vaccination, intravenous immunoglobulin …

Mitochondria-targeted delivery strategy of dual-loaded liposomes for Alzheimer's disease therapy

L Vasileva, G Gaynanova, F Valeeva… - International Journal of …, 2023 - mdpi.com
Liposomes modified with tetradecyltriphenylphosphonium bromide with dual loading of α-
tocopherol and donepezil hydrochloride were successfully designed for intranasal …

Epigenetic peripheral biomarkers for early diagnosis of Alzheimer's disease

C Villa, A Stoccoro - Genes, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and represents the
leading cause of cognitive impairment and dementia in older individuals throughout the …

Navigating the Intersection: Diabetes and Alzheimer's Intertwined Relationship

MB Kale, HM Bhondge, NL Wankhede… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) and Diabetes mellitus (DM) exhibit comparable
pathophysiological pathways. Genetic abnormalities in APP, PS-1, and PS-2 are linked to …