Neuroimaging has revolutionized our understanding of brain function and has become an
essential tool for researchers studying neurological disorders. Functional magnetic …

Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …

Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

Braak's hypothesis has been extremely influential over the last two decades. However,
neuropathological and clinical evidence suggest that the model does not conform to all …

Background Common genetic variance in apolipoprotein E (APOE), β‐glucocerebrosidase
(GBA), microtubule‐associated protein tau (MAPT), and α‐synuclein (SNCA) has been …

Neuroinflammation is a pathological change that is involved in the progression of
Parkinson's disease. Dysfunction of chaperone-mediated autophagy (CMA) has …

Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic
(Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S …

Objective Emerging pathological evidence suggests that there is an association between
glymphatic dysfunction and the progression of Parkinson's disease (PD). However, the …

Intensive physical activity improves motor functions in patients with Parkinson's disease (PD)
at early stages. However, the mechanisms underlying the beneficial effects of exercise on …

Objective To examine the association of midlife and late life multimorbidity, including
severity of multimorbidity, with incident dementia. Design Prospective cohort study. Setting …