Phenotypic switching of vascular smooth muscle cells in atherosclerosis
R Chen, DG McVey, D Shen, X Huang… - Journal of the American …, 2023 - Am Heart Assoc
The medial layer of the arterial wall is composed mainly of vascular smooth muscle cells
(VSMCs). Under physiological conditions, VSMCs assume a contractile phenotype, and their …
(VSMCs). Under physiological conditions, VSMCs assume a contractile phenotype, and their …
[HTML][HTML] Stem/Progenitor Cells and Related Therapy in Bronchopulmonary Dysplasia
M Marega, N El-Merhie, MY Gökyildirim, V Orth… - International journal of …, 2023 - mdpi.com
Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly seen in preterm
infants, and is triggered by infection, mechanical ventilation, and oxygen toxicity. Among …
infants, and is triggered by infection, mechanical ventilation, and oxygen toxicity. Among …
GLI1+ Cells Contribute to Vascular Remodeling in Pulmonary Hypertension
X Chu, V Kheirollahi, A Lingampally… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: The precise origin of newly formed ACTA2+ (alpha smooth muscle actin-
positive) cells appearing in nonmuscularized vessels in the context of pulmonary …
positive) cells appearing in nonmuscularized vessels in the context of pulmonary …
[HTML][HTML] Perinatal origins of bronchopulmonary dysplasia—deciphering normal and impaired lung development cell by cell
I Mižíková, B Thébaud - Molecular and Cellular Pediatrics, 2023 - Springer
Bronchopulmonary dysplasia (BPD) is a multifactorial disease occurring as a consequence
of premature birth, as well as antenatal and postnatal injury to the developing lung. BPD …
of premature birth, as well as antenatal and postnatal injury to the developing lung. BPD …
[HTML][HTML] WSB1, a Hypoxia-Inducible E3 Ligase, Promotes Myofibroblast Accumulation and Attenuates Alveolar Epithelial Regeneration in Mouse Lung Fibrosis
L Chong, L Zou, L Xiang, X Song, W Miao, X Yan… - The American Journal of …, 2024 - Elsevier
Idiopathic pulmonary fibrosis is a progressive interstitial lung disease for which there is no
curative therapy available. Repetitive alveolar epithelial injury repair, myofibroblast …
curative therapy available. Repetitive alveolar epithelial injury repair, myofibroblast …
[HTML][HTML] An Optimized Protocol for the Generation of Alveolospheres from Wild-Type Mice
M Zabihi, A Khadim, TM Schäfer, I Alexopoulos… - Cells, 2024 - mdpi.com
Organoid models have become an integral part of the research methodology in the lung
field. These systems allow for the study of progenitor and stem cell self-renewal, self …
field. These systems allow for the study of progenitor and stem cell self-renewal, self …
Fibroblast growth factor 10
F Rochais, RG Kelly - Differentiation, 2023 - Elsevier
Abstract Fibroblast growth factor 10 (FGF10) is a major morphoregulatory factor that plays
essential signaling roles during vertebrate multiorgan development and homeostasis …
essential signaling roles during vertebrate multiorgan development and homeostasis …
[PDF][PDF] The lung mesenchyme in development, regeneration, and fibrosis
E El Agha, VJ Thannickal - Journal of Clinical Investigation, 2023 - Am Soc Clin Investig
Mesenchymal cells are uniquely located at the interface between the epithelial lining and
the stroma, allowing them to act as a signaling hub among diverse cellular compartments of …
the stroma, allowing them to act as a signaling hub among diverse cellular compartments of …
Lung injury shifts pulmonary capillary endothelial cells towards regeneration-associated Lrg1+ subpopulations with delayed dynamics in aged mice
M Truchi, G Savary, H Cadis, K Lebrigand, A Baeri… - bioRxiv, 2023 - biorxiv.org
Introduction and main objectives: Idiopathic pulmonary fibrosis (IPF) is a chronic,
progressive and irreversible interstitial lung disease (ILD), that increases dramatically in …
progressive and irreversible interstitial lung disease (ILD), that increases dramatically in …