Hiplot: a comprehensive and easy-to-use web service for boosting publication-ready biomedical data visualization
Complex biomedical data generated during clinical, omics and mechanism-based
experiments have increasingly been exploited through cloud-and visualization-based data …
experiments have increasingly been exploited through cloud-and visualization-based data …
Manipulating mitochondrial electron flow enhances tumor immunogenicity
Although tumor growth requires the mitochondrial electron transport chain (ETC), the relative
contribution of complex I (CI) and complex II (CII), the gatekeepers for initiating electron flow …
contribution of complex I (CI) and complex II (CII), the gatekeepers for initiating electron flow …
Correlations between spatial sampling biases and environmental niches affect species distribution models
DJ Baker, IMD Maclean, M Goodall… - Global Ecology and …, 2022 - Wiley Online Library
Aim Spatial sampling biases in biodiversity data arise because of complex interactions
between geography, species characteristics and human behaviour, including preferences …
between geography, species characteristics and human behaviour, including preferences …
TLimmuno2: predicting MHC class II antigen immunogenicity through transfer learning
Major histocompatibility complex (MHC) class II molecules play a pivotal role in antigen
presentation and CD4+ T cell response. Accurate prediction of the immunogenicity of MHC …
presentation and CD4+ T cell response. Accurate prediction of the immunogenicity of MHC …
[HTML][HTML] A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer
Y Wei, H Zhang, Q Feng, S Wang, Y Shao, J Wu… - Cell death & …, 2022 - nature.com
Adenosine (A) to inosine (I) RNA editing catalyzed by adenosine deaminases acting on
RNA (ADAR) enzymes is a post-transcriptional modification that emerged as a key player in …
RNA (ADAR) enzymes is a post-transcriptional modification that emerged as a key player in …
[HTML][HTML] Extrachromosomal DNA formation enables tumor immune escape potentially through regulating antigen presentation gene expression
Extrachromosomal DNA (ecDNA) is a type of circular and tumor specific genetic element.
EcDNA has been reported to display open chromatin structure, facilitate oncogene …
EcDNA has been reported to display open chromatin structure, facilitate oncogene …
[HTML][HTML] Comprehensive pan-cancer analysis reveals NUSAP1 is a novel predictive biomarker for prognosis and immunotherapy response
H Zheng, M Wang, S Zhang, D Hu, Q Yang… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Nucleolar and spindle-associated protein 1 (NUSAP1) is a microtubule-associated protein
that plays a crucial role in mitosis. Despite initial reports suggesting a potential involvement …
that plays a crucial role in mitosis. Despite initial reports suggesting a potential involvement …
[HTML][HTML] Association between atopic dermatitis and colorectal cancer: TET2 as a shared gene signature and prognostic biomarker
ZQ Zhan, ZM Huang, RQ Zeng, YH Luo, ZX Xie… - Journal of …, 2024 - ncbi.nlm.nih.gov
Background: Recent studies have linked atopic dermatitis (AD) to colorectal cancer (CRC)
risk. Their causality and potential molecular mechanisms remain unclear. Methods: We …
risk. Their causality and potential molecular mechanisms remain unclear. Methods: We …
[HTML][HTML] myCMIE: My cancer molecular information exchange
Q Xu, J Kowalski - Iscience, 2023 - cell.com
Molecular profiling reports (MPRs) are critical for determining treatment options for cancer
patients. They include several pages of information on genomic findings, drugs, and trial …
patients. They include several pages of information on genomic findings, drugs, and trial …
IBPGNET: lung adenocarcinoma recurrence prediction based on neural network interpretability
Z Xu, H Liao, L Huang, Q Chen, W Lan… - Briefings in …, 2024 - academic.oup.com
Lung adenocarcinoma (LUAD) is the most common histologic subtype of lung cancer. Early-
stage patients have a 30–50% probability of metastatic recurrence after surgical treatment …
stage patients have a 30–50% probability of metastatic recurrence after surgical treatment …