Cannabidiol, neuroprotection and neuropsychiatric disorders

AC Campos, MV Fogaça, AB Sonego… - Pharmacological …, 2016 - Elsevier
Cannabidiol (CBD) is a non-psychotomimetic phytocannabinoid derived from Cannabis
sativa. It has possible therapeutic effects over a broad range of neuropsychiatric disorders …

Cannabidiol (CBD) use in psychiatric disorders: A systematic review

S Bonaccorso, A Ricciardi, C Zangani, S Chiappini… - Neurotoxicology, 2019 - Elsevier
Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …

The role of glutamate receptors in epilepsy

TS Chen, TH Huang, MC Lai, CW Huang - Biomedicines, 2023 - mdpi.com
Glutamate is an essential excitatory neurotransmitter in the central nervous system, playing
an indispensable role in neuronal development and memory formation. The dysregulation of …

The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease

A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis
which exhibits potential beneficial properties in a wide range of diseases, including …

Cellular mechanisms of melatonin: insight from neurodegenerative diseases

D Chen, T Zhang, TH Lee - Biomolecules, 2020 - mdpi.com
Neurodegenerative diseases are the second most common cause of death and
characterized by progressive impairments in movement or mental functioning in the central …

Cannabidiol as a promising strategy to treat and prevent movement disorders?

FF Peres, AC Lima, JEC Hallak, JA Crippa… - Frontiers in …, 2018 - frontiersin.org
Movement disorders such as Parkinson's disease and dyskinesia are highly debilitating
conditions linked to oxidative stress and neurodegeneration. When available, the …

[HTML][HTML] The role of cannabinoids in neuroanatomic alterations in cannabis users

V Lorenzetti, N Solowij, M Yücel - Biological psychiatry, 2016 - Elsevier
The past few decades have seen a marked change in the composition of commonly smoked
cannabis. These changes primarily involve an increase of the psychoactive compound∆ 9 …

Plastic and neuroprotective mechanisms involved in the therapeutic effects of cannabidiol in psychiatric disorders

AC Campos, MV Fogaça, FF Scarante… - Frontiers in …, 2017 - frontiersin.org
Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric
disorders, including anxiety, psychosis, and depression. The mechanisms responsible for …

Neuroprotection of cannabidiol, its synthetic derivatives and combination preparations against microglia-mediated neuroinflammation in neurological disorders

M Yousaf, D Chang, Y Liu, T Liu, X Zhou - Molecules, 2022 - mdpi.com
The lack of effective treatment for neurological disorders has encouraged the search for
novel therapeutic strategies. Remarkably, neuroinflammation provoked by the activated …

Molecular targets of cannabidiol in experimental models of neurological disease

S Silvestro, G Schepici, P Bramanti, E Mazzon - Molecules, 2020 - mdpi.com
Cannabidiol (CBD) is a non-psychoactive phytocannabinoid known for its beneficial effects
including antioxidant and anti-inflammatory properties. Moreover, CBD is a compound with …