[HTML][HTML] Mangosteen for malignancy prevention and intervention: Current evidence, molecular mechanisms, and future perspectives

LS Kalick, HA Khan, E Maung, Y Baez… - Pharmacological …, 2023 - Elsevier
Abstract Mangosteen (Garcinia mangostana L.), also known as the “queen of fruits”, is a
tropical fruit of the Clusiacea family. While native to Southeast Asian countries, such as …

Recent updates on metabolite composition and medicinal benefits of mangosteen plant

WM Aizat, IN Jamil, FH Ahmad-Hashim, NM Noor - PeerJ, 2019 - peerj.com
Background Mangosteen (Garcinia mangostana L.) fruit has a unique sweet-sour taste and
is rich in beneficial compounds such as xanthones. Mangosteen originally been used in …

[PDF][PDF] Chemical compounds and pharmacological activities of mangosteen (Garcinia mangostana L.)—Updated review

D Rizaldy, R Hartati, T Nadhifa… - … Res. Appl. Chem, 2021 - biointerfaceresearch.com
Mangosteen (Garcinia mangostana L.) is a tropical fruit belonging to Guttiferae (syn.
Clusiaceae) family. Research on mangosteen has been widely conducted. Also, numerous …

New Alpha-Amylase Inhibitory Metabolites from Pericarps of Garcinia mangostana

NA Alhakamy, GA Mohamed, UA Fahmy, BG Eid… - Life, 2022 - mdpi.com
Two new benzophenones: garcimangophenones A (6) and B (7) and five formerly reported
metabolites were purified from the pericarps EtOAc fraction of Garcinia mangostana ((GM) …

Mangosteen metabolites as promising alpha-amylase inhibitor candidates: in silico and in vitro evaluations

AM Omar, DF AlKharboush, KA Mohammad… - Metabolites, 2022 - mdpi.com
Diabetes is a chronic metabolic disorder characterized by raised glucose levels in the blood,
resulting in grave damage over time to various body organs, including the nerves, heart …

[HTML][HTML] Mangostanaxanthone VIIII, a new xanthone from Garcinia mangostana pericarps, α-amylase inhibitory activity, and molecular docking studies

SRM Ibrahim, GA Mohamed, MT Khayat… - Revista Brasileira de …, 2019 - SciELO Brasil
ABSTRACT A new xanthone: mangostanaxanthone VIIII [1, 3, 5, 6, 7-pentahydroxy-2-(3-
methylbut-2-enyl)-8-(3-hydroxy-3-methylbut-1-enyl) xanthone](5) and four known xanthones …

Alpha‐Mangostin Activates MOAP‐1 Tumor Suppressor and Mitochondrial Signaling in MCF‐7 Human Breast Cancer Cells

SE Simon, HS Lim, FA Jayakumar… - Evidence‐Based …, 2022 - Wiley Online Library
α‐Mangostin, one of the major constituents of Garcinia mangostana, has been reported to
possess several biological activities, including antioxidant, anti‐inflammatory, antibacterial …

Protective activity of tovophyllin A, a xanthone isolated from Garcinia mangostana pericarps, against acetaminophen-induced liver damage: role of Nrf2 activation

SRM Ibrahim, DS El-Agamy, HM Abdallah, N Ahmed… - Food & Function, 2018 - pubs.rsc.org
Garcinia mangostana L.(GM, family Guttiferae) is one of the most widely recognized tropical
fruits. GM is a wealthy pool of xanthones that exhibit a wide range of bioactivities …

Garcixanthones B and C, new xanthones from the pericarps of Garcinia mangostana and their cytotoxic activity

SRM Ibrahim, HM Abdallah, AM El-Halawany… - Phytochemistry …, 2018 - Elsevier
Two new prenylated xanthones, garcixanthones B (1) and C (2) and six known metabolites:
gartanin (3), 1, 3, 8-trihydroxy-2-(3-methyl-2-butenyl)-4-(3-hydroxy-3-methylbutanoyl) …

Naturally Occurring Xanthones; Biological Activities, Chemical Profiles and In Silico Drug Discovery

HR El-Seedi, HMS Ibrahim, N Yosri… - Current Medicinal …, 2024 - benthamdirect.com
Xanthones are widely distributed polyphenols, present commonly in higher plants; Garcinia,
Calophyllum, Hypericum, Platonia, Mangifera, Gentiana and Swertia. Xanthone tricyclic …