Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Interleukin (IL)-33 belongs to IL-1 cytokine family which is constitutively produced from the
structural and lining cells including fibroblasts, endothelial cells, and epithelial cells of skin …

Mast cells are important effector cells of the immune system and recent studies show that
they have immunomodulatory roles in diverse processes in both health and disease. Mast …

Since first described by Paul Ehrlich in 1878, mast cells have been mostly viewed as
effectors of allergy. It has been only in the past two decades that mast cells have gained …

Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the
pathophysiology of anaphylaxis and other acute allergic reactions that it can be difficult to …

Mast cells and their mediators have been implicated in the pathogenesis of asthma and
allergy for decades. Allergic asthma is a complex chronic lung disease in which several …

Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Mast cells and basophils are potent effector cells of the innate immune system, and they
have both beneficial and detrimental functions for the host. They are mainly implicated in pro …

Chronic rhinosinusitis (CRS) is one of the most common chronic diseases worldwide. It is a
heterogeneous disease, and geographical or ethnic differences in inflammatory pattern in …

Mast cells are widely distributed in tissues, particularly near surfaces exposed to the
environment. Mast cells can be activated to secrete diverse mediators and cytokines by IgE …