Polarity establishment, asymmetric division and segregation of fate determinants in early C. elegans embryos
Polarity establishment, asymmetric division, and acquisition of cell fates are critical steps
during earlydevelopment. In this review, we discuss processes that set up the embryonic …
during earlydevelopment. In this review, we discuss processes that set up the embryonic …
Magnetic measurement and stimulation of cellular and intracellular structures
From single-pole magnetic tweezers to robotic magnetic-field generation systems, the
development of magnetic micromanipulation systems, using electromagnets or permanent …
development of magnetic micromanipulation systems, using electromagnets or permanent …
Apical constriction drives tissue-scale hydrodynamic flow to mediate cell elongation
B He, K Doubrovinski, O Polyakov, E Wieschaus - Nature, 2014 - nature.com
Epithelial folding mediated by apical constriction converts flat epithelial sheets into
multilayered, complex tissue structures and is used throughout development in most …
multilayered, complex tissue structures and is used throughout development in most …
Supracellular migration–beyond collective cell migration
A Shellard, R Mayor - Journal of cell science, 2019 - journals.biologists.com
Collective cell migration is a highly complex process in which groups of cells move together.
A fundamental question is how cell ensembles can migrate efficiently. In some cases, the …
A fundamental question is how cell ensembles can migrate efficiently. In some cases, the …
The dynamics of microtubule/motor-protein assemblies in biology and physics
MJ Shelley - Annual review of fluid mechanics, 2016 - annualreviews.org
Many important processes in the cell are mediated by stiff microtubule polymers and the
active motor proteins moving on them. This includes the transport of subcellular structures …
active motor proteins moving on them. This includes the transport of subcellular structures …
How active mechanics and regulatory biochemistry combine to form patterns in development
The development of organisms starting from their zygotic state involves a tight integration of
the myriad biochemical signaling interactions with the mechanical forces that eventually …
the myriad biochemical signaling interactions with the mechanical forces that eventually …
Go with the flow–bulk transport by molecular motors
W Lu, VI Gelfand - Journal of cell science, 2023 - journals.biologists.com
Cells are the smallest building blocks of all living eukaryotic organisms, usually ranging from
a couple of micrometers (for example, platelets) to hundreds of micrometers (for example …
a couple of micrometers (for example, platelets) to hundreds of micrometers (for example …
Size-and position-dependent cytoplasm viscoelasticity through hydrodynamic interactions with the cell surface
J Najafi, S Dmitrieff, N Minc - Proceedings of the National …, 2023 - National Acad Sciences
Many studies of cytoplasm rheology have focused on small components in the
submicrometer scale. However, the cytoplasm also baths large organelles like nuclei …
submicrometer scale. However, the cytoplasm also baths large organelles like nuclei …
Two-fluid dynamics and micron-thin boundary layers shape cytoplasmic flows in early Drosophila embryos
Cytoplasmic flows are widely emerging as key functional players in development. In early
Drosophila embryos, flows drive the spreading of nuclei across the embryo. Here, we …
Drosophila embryos, flows drive the spreading of nuclei across the embryo. Here, we …
Patterning and polarization of cells by intracellular flows
R Illukkumbura, T Bland, NW Goehring - Current opinion in cell biology, 2020 - Elsevier
Beginning with Turing's seminal work [1], decades of research have demonstrated the
fundamental ability of biochemical networks to generate and sustain the formation of …
fundamental ability of biochemical networks to generate and sustain the formation of …