Vaccines meet big data: State-of-the-Art and future prospects. From the classical 3Is (“Isolate–Inactivate–Inject”) vaccinology 1.0 to vaccinology 3.0, vaccinomics, and …

NL Bragazzi, V Gianfredi, M Villarini… - Frontiers in public …, 2018 - frontiersin.org
Vaccines are public health interventions aimed at preventing infections-related mortality,
morbidity, and disability. While vaccines have been successfully designed for those …

Update on non-typeable Haemophilus influenzae-mediated disease and vaccine development

F Jalalvand, K Riesbeck - Expert review of vaccines, 2018 - Taylor & Francis
ABSTRACT Introduction: Non-typeable Haemophilus influenzae (NTHi) has attracted more
interest in recent years due to an increased prevalence of infections caused by the …

Immunoinformatics Approach to Design a Novel Epitope-Based Oral Vaccine Against Helicobacter pylori

VH Urrutia-Baca, R Gomez-Flores… - Journal of …, 2019 - liebertpub.com
Helicobacter pylori is an infectious agent that colonizes the gastric mucosa of half of the
population worldwide. This bacterium has been recognized as belonging to group 1 …

Proteomics approaches: A review regarding an importance of proteome analyses in understanding the pathogens and diseases

M Zubair, J Wang, Y Yu, M Faisal, M Qi… - Frontiers in Veterinary …, 2022 - frontiersin.org
Proteomics is playing an increasingly important role in identifying pathogens, emerging and
re-emerging infectious agents, understanding pathogenesis, and diagnosis of diseases …

An overview on enrichment methods for cell surface proteome profiling

Y Li, H Qin, M Ye - Journal of separation science, 2020 - Wiley Online Library
Cell surface proteins are essential for many important biological processes, including cell–
cell interactions, signal transduction, and molecular transportation. With the characteristics of …

Comprehending B-cell epitope prediction to develop vaccines and immunodiagnostics

SEC Caoili - Frontiers in Immunology, 2022 - frontiersin.org
B-cell epitope prediction (BCEP) is the original subject of immunoinformatics (ie,
bioinformatics applied to immunology). This began with protein sequence analysis to identify …

The Mycoplasma spp. 'Releasome': A New Concept for a Long-Known Phenomenon

P Gaurivaud, F Tardy - Frontiers in Microbiology, 2022 - frontiersin.org
The bacterial secretome comprises polypeptides expressed at the cell surface or released
into the extracellular environment as well as the corresponding secretion machineries …

Comparative Proteomic Analysis of Secretory Proteins of Mycoplasma bovis and Mycoplasma mycoides subsp. mycoides Investigates Virulence and Discovers …

AS Dawood, G Zhao, Y He, D Lu, S Wang, H Zhang… - Veterinary …, 2023 - mdpi.com
Simple Summary Mycoplasma bovis (M. bovis) and Mycoplasma mycoides subsp. mycoides
(Mmm) are the most important pathogenic mycoplasma species. But, the limited knowledge …

Identification of conserved Mycoplasma agalactiae surface antigens by immunoproteomics

C Cacciotto, MF Addis, D Pagnozzi… - Veterinary Immunology …, 2021 - Elsevier
Contagious agalactia represents one of the most relevant infectious diseases of dairy sheep,
with Mycoplasma agalactiae being the primary etiological agent. The early, sensitive, and …

Novel vaccine design based on genomics data analysis: A review

G Lu, S Shan, B Zainab, Z Ayaz, J He… - Scandinavian …, 2021 - Wiley Online Library
Modification of pathogenic strains with the passage of time is responsible for evolution in the
timeline of vaccine development for last 30 years. Recent advancements in computational …