Natriuretic peptides in cardiovascular diseases: current use and perspectives

M Volpe, S Rubattu, J Burnett Jr - European heart journal, 2014 - academic.oup.com
The natriuretic peptides (NPs) family, including atrial, B-type, and C-type NPs, is a group of
hormones possessing relevant haemodynamic and anti-remodelling actions in the …

Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure

S Fu, P Ping, F Wang, L Luo - Journal of biological engineering, 2018 - Springer
As a family of hormones with pleiotropic effects, natriuretic peptide (NP) system includes
atrial NP (ANP), B-type NP (BNP), C-type NP (CNP), dendroaspis NP and urodilatin, with NP …

Cardiovascular pleiotropic effects of natriuretic peptides

M Forte, M Madonna, S Schiavon, V Valenti… - International journal of …, 2019 - mdpi.com
Atrial natriuretic peptide (ANP) is a cardiac hormone belonging to the family of natriuretic
peptides (NPs). ANP exerts diuretic, natriuretic, and vasodilatory effects that contribute to …

[HTML][HTML] Natriuretic peptides and cardio-renal disease

M Volpe - International journal of cardiology, 2014 - Elsevier
The natriuretic peptide (NP) system is an important endocrine, autocrine and paracrine
system, consisting of a family of peptides which provide cardiac, renal and vascular effects …

Natriuretic peptides in human heart: Novel insight into their molecular forms, functions, and diagnostic use

A Matsuo, C Nagai-Okatani, M Nishigori, K Kangawa… - Peptides, 2019 - Elsevier
Among the three natriuretic peptides, atrial/A-type natriuretic peptide (ANP) and brain/B-type
natriuretic peptide (BNP) are primarily produced by, and secreted from, heart tissue. They …

Natriuretic peptides and cardiometabolic health

DK Gupta, TJ Wang - Circulation Journal, 2015 - jstage.jst.go.jp
Natriuretic peptides are cardiac-derived hormones with a range of protective functions,
including natriuresis, diuresis, vasodilation, lusitropy, lipolysis, weight loss, and improved …

The endocrine function of the heart: physiology and involvements of natriuretic peptides and cyclic nucleotide phosphodiesterases in heart failure

C Lugnier, A Meyer, A Charloux, E Andrès… - Journal of clinical …, 2019 - mdpi.com
Besides pumping, the heart participates in hydro-sodium homeostasis and systemic blood
pressure regulation through its endocrine function mainly represented by the large family of …

NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice

C Cheng, J Zhang, X Li, F Xue, L Cao, L Meng… - … and Targeted Therapy, 2023 - nature.com
Previous studies suggested a beneficial effect of natriuretic peptides in animal models of
cardiovascular disease, but the role of natriuretic peptide receptor C (NPRC) in the …

Atrial natriuretic peptide: an old hormone or a new cytokine?

P De Vito - Peptides, 2014 - Elsevier
Atrial natriuretic peptide (ANP) a cardiovascular hormone mainly secreted by heart atria in
response to stretching forces induces potent diuretic, natriuretic and vasorelaxant effects …

Molecular mechanisms underlying cardiac antihypertrophic and antifibrotic effects of natriuretic peptides

C Calvieri, S Rubattu, M Volpe - Journal of molecular medicine, 2012 - Springer
Natriuretic peptides (NPs) exert well-characterized protective effects on the cardiovascular
system, such as vasorelaxation, natri-and diuresis, increase of endothelial permeability, and …