Parkinson disease (PD) is a progressive disorder characterized by dopaminergic
neurodegeneration in the brain. The development of parkinsonism is preceded by a long …

Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

A major challenge in Parkinson's disease is the variability in symptoms and rates of
progression, underpinned by heterogeneity of pathological processes. Biomarkers are …

Quantitative susceptibility mapping (QSM), one of the advanced MRI techniques for
evaluating magnetic susceptibility, offers precise quantitative measurements of spatial …

Parkinson's disease (PD) is a clinically heterogeneous chronic progressive neuro-
degenerative disease with loss of dopaminergic neurons in the nigrosome 1 (N1) territory of …

Recently, deep neural network-powered quantitative susceptibility mapping (QSM), QSMnet,
successfully performed ill-conditioned dipole inversion in QSM and generated high-quality …

Background: Parkinson's disease (PD) is a progressive neurodegenerative disease whose
main neuropathological feature is the loss of dopaminergic neurons of the substantia nigra …

Introduction There is currently no definitive diagnostic test for Parkinson's disease (PD) and
the current diagnostic procedure primarily relies on clinical manifestations. A hypointense …

Parkinson's disease (PD) is a common neurodegenerative disease, and apart from a few
rare genetic causes, its pathogenesis remains largely unclear. Recent scientific interest has …

Introduction: The loss of nigrosome-1, which is also referred to as the swallow tail sign (STS)
in T2*-weighted iron-sensitive magnetic resonance imaging (MRI), has recently emerged as …