Targeting cardiovascular inflammation: next steps in clinical translation

PR Lawler, DL Bhatt, LC Godoy… - European heart …, 2021 - academic.oup.com
Systemic vascular inflammation plays multiple maladaptive roles which contribute to the
progression and destabilization of atherosclerotic cardiovascular disease (ASCVD). These …

National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary …

NACB Writing Group Members, DA Morrow… - Circulation, 2007 - Am Heart Assoc
This article has been copublished in the April issue of Clinical Chemistry (Volume 53,
Number 4, 2007). 1 Brigham and Women's Hospital, Harvard University, Boston, MA. 2 …

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

PM Ridker, CH Hennekens, JE Buring… - New England journal of …, 2000 - Mass Medical Soc
Background Since inflammation is believed to have a role in the pathogenesis of
cardiovascular events, measurement of markers of inflammation has been proposed as a …

Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men

PM Ridker, N Rifai, MJ Stampfer, CH Hennekens - Circulation, 2000 - Am Heart Assoc
Background—Interleukin-6 (IL-6) plays a central role in inflammation and tissue injury.
However, epidemiological data evaluating the role of IL-6 in atherogenesis are sparse …

Cardiogenic shock complicating acute myocardial infarction: expanding the paradigm

JS Hochman - Circulation, 2003 - Am Heart Assoc
2998 dilated cardiomyopathy and mild to moderate chronic CHF often have EFs
considerably lower than this and are not in shock. 12 These observations highlight the role …

Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor

S Wassmann, M Stumpf, K Strehlow, A Schmid… - Circulation …, 2004 - Am Heart Assoc
Angiotensin II type 1 (AT1) receptor activation as well as proinflammatory cytokines such as
interleukin-6 (IL-6) are involved in the development and progression of atherosclerosis. The …

High-sensitivity C-reactive protein: clinical importance

SS Bassuk, N Rifai, PM Ridker - Current problems in cardiology, 2004 - Elsevier
High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation that predicts incident
myocardial infarction, stroke, peripheral arterial disease, and sudden cardiac death among …

C-reactive protein and other inflammatory risk markers in acute coronary syndromes

GJ Blake, PM Ridker - Journal of the American College of Cardiology, 2003 - jacc.org
Markers of myocyte necrosis such as cardiac troponin or creatine kinase-myocardial band
are invaluable tools for risk stratification among patients presenting with acute coronary …

Circulating markers of inflammation and atherosclerosis

L Lind - Atherosclerosis, 2003 - Elsevier
Atherosclerosis is nowadays generally accepted as an inflammatory disease. It is known that
local inflammation occurs in the formation the plaques, as macrophages and other immuno …

Systemic inflammatory response syndrome after acute myocardial infarction complicated by cardiogenic shock

S Kohsaka, V Menon, AM Lowe, M Lange… - Archives of internal …, 2005 - jamanetwork.com
Background The role of inflammation in patients with coronary artery disease is emerging.
We sought to assess the profile and outcomes of patients with a clinical syndrome of severe …