Ultrasound-based micro-/nanosystems for biomedical applications

H Huang, Y Zheng, M Chang, J Song, L Xia… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Strategies to engineer various nanocarrier-based hybrid catalysts for enhanced chemodynamic cancer therapy

JN Hao, K Ge, G Chen, B Dai, Y Li - Chemical Society Reviews, 2023 - pubs.rsc.org
Chemodynamic therapy (CDT) is a newly developed cancer-therapeutic modality that kills
cancer cells by the highly toxic hydroxyl radical (˙ OH) generated from the in situ triggered …

Synergistic Interaction between Metal Single‐Atoms and Defective WO3−x Nanosheets for Enhanced Sonodynamic Cancer Therapy

Z Zhou, T Wang, T Hu, H Xu, L Cui, B Xue… - Advanced …, 2024 - Wiley Online Library
Although metal single‐atom (SA)‐based nanomaterials are explored as sonosensitizers for
sonodynamic therapy (SDT), they normally exhibit poor activities and need to combine with …

A multifunctional covalent organic framework nanozyme for promoting ferroptotic radiotherapy against esophageal cancer

LL Zhou, Q Guan, W Zhou, JL Kan, K Teng, M Hu… - ACS …, 2023 - ACS Publications
Radiotherapy is inevitably accompanied by some degree of radiation resistance, which
leads to local recurrence and even therapeutic failure. To overcome this limitation, herein …

Oxygen‐Vacancy‐Engineered W18O49−x Nanobrush with a Suitable Band Structure for Highly Efficient Sonodynamic Therapy

P Zheng, Y Ami'erjiang, B Liu, M Wang… - Angewandte …, 2024 - Wiley Online Library
With the rapid development of external minimally invasive or noninvasive therapeutic
modalities, ultrasound‐based sonodynamic therapy (SDT) is a new alternative for treating …

Covalent organic framework nanoparticles: Overcoming the challenges of hypoxia in cancer therapy

N Singh, M Won, Y Xu, C Yoon, J Yoo, M Li… - Coordination Chemistry …, 2024 - Elsevier
Hypoxia, or low oxygen levels, is a common feature of the tumor microenvironment. It is
caused by the aggressive proliferation of cancer cells, which consume more oxygen than …

Exosome‐Inhibiting Polymeric Sonosensitizer for Tumor‐Specific Sonodynamic Immunotherapy

J Wu, J Huang, J Yu, M Xu, J Liu, K Pu - Advanced Materials, 2024 - Wiley Online Library
Combination cancer immunotherapy based on electromagnetic energy and immunotherapy
shows potent anti‐cancer efficacy. However, as a factor that mediates tumor metastasis and …

Sonocatalytic Cancer Therapy: Theories, Advanced Catalyst and System Design

R Li, X Wang, J Shi, Y Kang, X Ji - Nanoscale, 2023 - pubs.rsc.org
Treating cancer remains one of the most formidable challenges in modern medicine, with
traditional treatment options often being limited by poor therapeutic outcomes and …

pH-Responsive injectable self-healing hydrogels loading Au nanoparticles-decorated bimetallic organic frameworks for synergistic sonodynamic-chemodynamic …

S Xu, H Zhang, Z Qian, W Yuan - Journal of Colloid and Interface Science, 2024 - Elsevier
A novel and efficient cancer therapy was developed using a smart hydrogel containing
multifunctional bimetallic organic frameworks and anticancer drugs. The injectable self …

Copper Single-Atom-Based Metal–Organic Framework for Ultrasound-Enhanced Nanocatalytic Therapy

H Wang, Z Zhang, X Wang, X Jin, X Gao, L Yu… - Nano Letters, 2024 - ACS Publications
Chemodynamic therapy (CDT) is an emerging therapeutic modality triggered by
endogenous substances in the tumor microenvironment (TME) to generate reactive oxygen …