The quest for alternative drugs to the well-known cisplatin and its derivatives, which are still
used in more than 50% of the treatment regimes for patients suffering from cancer, is highly …

The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …

Metal complexes with N-heterocyclic carbene (NHC) ligands are widely used in chemistry
due to their catalytic properties and applied for olefin metathesis among other reactions. The …

The chemistry of heterocyclic carbenes has experienced a rapid development over the last
years. In addition to the imidazolin‐2‐ylidenes, a large number of cyclic diaminocarbenes …

This tutorial review compiles the advances that have been achieved in using transition metal
complexes containing N-heterocyclic carbene ligands as components for materials …

Ofele and Wanzlick reported the synthesis of the first N-heterocyclic carbene (NHC)-metal
complexes in 1968. 1, 2 The isolation of the first free carbene by Arduengo in 1991 set the …

An N-heterocyclic carbene (NHC) contains a carbene carbon incorporated in a nitrogen-
containing heterocycle, presumably reactive and difficult to isolate. 1 The first isolation of …

The continuous growth of N-heterocyclic carbene (NHC) chemistry is a fact that is pointed
out in all the introductions of the publications regarding NHCs that have appeared in the …

Complete synthetic, structural, and biomedical studies of two Pd complexes as well as Au
and Ag complexes of 1-benzyl-3-tert-butylimidazol-2-ylidene are reported. Specifically, trans …

We provide an overview on the state‐of‐the‐art in transition‐metal complexes formed with
water‐soluble NHC ligands. Paths to introducing water solubility by ligand design are …