Background The widespread use of the integrase strand transfer inhibitor (INSTI)
dolutegravir in first-line and second-line antiretroviral therapy (ART) might facilitate …

To curb HIV infection rate in Tanzania, antiretroviral therapy (ART) has been scaled up since
2006, and in 2019, the country shifted to regimen including dolutegravir as a default first line …

Background: There are an increasing number of articles focused on the prevalence and
clinical impact of pretreatment HIV drug resistance (PDR) detected by Sanger sequencing …

After a decade of dolutegravir (DTG) use in various antiretroviral therapy combinations and
in diverse populations globally, it is critical to identify HIV strains with reduced drug …

To evaluate the prevalence of transmitted drug resistance (TDR) to nucleoside and
nonnucleoside reverse transcriptase inhibitors (NRTI, NNRTI), protease inhibitors (PI), and …

Background Integrase strand transfer inhibitors (INSTIs) are recommended as first-line ART
for people living with HIV (PLWH) in most guidelines. The INSTI-resistance-associated …

The surveillance of drug resistance in the HIV-1 naïve population remains critical to
optimizing the effectiveness of antiretroviral therapy (ART), mainly in the era of integrase …

Background Transmitted drug resistance (TDR) is still a critical aspect for the management
of individuals living with HIV-1. Thus, its evaluation is crucial to optimize HIV care. Methods …

Background A rapid ART initiation approach can be beneficial in people with advanced HIV
disease, in consideration of their high morbidity and mortality. The aim of our study was to …

Molecular epidemiology of HIV-1 infection is challenging due to the highly diverse HIV-
genome. We investigated the genetic diversity and prevalence of transmitted drug resistance …