Emodin-A natural anthraquinone derivative with diverse pharmacological activities

RB Semwal, DK Semwal, S Combrinck, A Viljoen - Phytochemistry, 2021 - Elsevier
Abstract Emodin (1, 3, 8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone
derivative that is present in numerous globally renowned herbal medicines. It is recognised …

Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology

SU Chun-Yan, M Qian-Liang, K Rahman… - Chinese journal of …, 2015 - Elsevier
Salvia miltiorrhiza Bunge (SM) is a very popular medicinal plant that has been extensively
applied for many years to treat various diseases, especially coronary heart diseases and …

Targeting renal fibrosis: mechanisms and drug delivery systems

MV Nastase, J Zeng-Brouwers, M Wygrecka… - Advanced drug delivery …, 2018 - Elsevier
Renal fibrosis is the common outcome of many chronic kidney diseases (CKD) independent
of the underlying etiology. Despite a host of promising experimental data, currently available …

Ketones and lactate “fuel” tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

G Bonuccelli, A Tsirigos, D Whitaker-Menezes… - Cell cycle, 2010 - Taylor & Francis
Previously, we proposed a new model for understanding the" Warburg effect" in tumor
metabolism. In this scheme, cancer-associated fibroblasts undergo aerobic glycolysis and …

Oral submucous fibrosis: an update

U Wollina, SB Verma, FM Ali, K Patil - Clinical, cosmetic and …, 2015 - Taylor & Francis
Oral submucous fibrosis (OSF) is a premalignant condition caused by betel chewing. It is
very common in Southeast Asia but has started to spread to Europe and North America. OSF …

Berberine inhibits Smad and non-Smad signaling cascades and enhances autophagy against pulmonary fibrosis

P Chitra, G Saiprasad, R Manikandan… - Journal of molecular …, 2015 - Springer
Idiopathic pulmonary fibrosis (IPF) is a fibroproliferative lung disorder of unknown aetiology.
Transforming growth factor-β1 (TGF-β1)-mediated Smad and non-Smad signaling cascades …

[HTML][HTML] Why is research on herbal medicinal products important and how can we improve its quality?

O Pelkonen, Q Xu, TP Fan - Journal of Traditional and Complementary …, 2014 - Elsevier
Research on herbal medicinal products is increasingly published in “Western” scientific
journals dedicated primarily to conventional medicines. Publications are concerned mainly …

Quercetin inhibits kidney fibrosis and the epithelial to mesenchymal transition of the renal tubular system involving suppression of the Sonic Hedgehog signaling …

X Liu, N Sun, N Mo, S Lu, E Song, C Ren, Z Li - Food & function, 2019 - pubs.rsc.org
Quercetin is the most ubiquitous flavonoid in fruits, herbs, vegetables and products made
from them. It shows the potential to inhibit the progression of kidney fibrosis and the …

Baicalin attenuates inflammation by inhibiting NF-κB activation in cigarette smoke induced inflammatory models

Z Lixuan, D Jingcheng, Y Wenqin, H Jianhua… - Pulmonary …, 2010 - Elsevier
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a key player in the
inflammatory response. Baicalin is an extract from roots of the plant scutellaria baicalensis …

Therapeutic and delivery strategies of phytoconstituents for renal fibrosis

H Xu, T Wu, L Huang - Advanced drug delivery reviews, 2021 - Elsevier
Chronic kidney disease (CKD) is one of the most common diseases endangering human
health and life. By 2030, 14 per 100,000 people may die from CKD. Renal fibrosis (RF) is an …