The protein tyrosine phosphorylation during in vitro capacitation and cryopreservation of mammalian spermatozoa

S Naresh, SK Atreja - Cryobiology, 2015 - Elsevier
Before the process of fertilization, spermatozoa necessitate a period of residence in the
female reproductive environment, and undergo a sequence of physiological and …

Shedding light on the role of cAMP in mammalian sperm physiology

M Balbach, V Beckert, JN Hansen… - Molecular and cellular …, 2018 - Elsevier
Mammalian fertilization relies on sperm finding the egg and penetrating the egg vestments.
All steps in a sperm's lifetime crucially rely on changes in the second messenger cAMP …

Loss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrity

SE Fiedler, T Dudiki, S Vijayaraghavan… - Biology of …, 2013 - academic.oup.com
The fibrous sheath (FS) is a flagellar cytoskeletal structure unique to sperm that surrounds
the outer dense fibers and axoneme. Its primary components are A-kinase anchoring …

CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa

SAM Young, H Miyata, Y Satouh… - Journal of cell …, 2016 - journals.biologists.com
ABSTRACT Ca2+-binding tyrosine-phosphorylation-regulated protein (CABYR) has been
implicated in sperm physiological function in several in vitro studies. It has also been …

[HTML][HTML] Quantitative phosphoproteomics analyses reveal the regulatory mechanisms related to frozen-thawed sperm capacitation and acrosome reaction in yak (Bos …

R Zhang, C Liang, X Guo, P Bao, J Pei, F Wu… - Frontiers in …, 2022 - frontiersin.org
Mammalian spermatozoa are not mature after ejaculation and must undergo additional
functional and structural changes within female reproductive tracts to achieve subsequent …

Calcium regulates motility and protein phosphorylation by changing cAMP and ATP concentrations in boar sperm in vitro

X Li, L Wang, Y Li, N Zhao, L Zhen, J Fu… - Animal reproduction …, 2016 - Elsevier
Considering the importance of calcium (Ca 2+) in regulating sperm capacitation,
hyperactivation and acrosome reaction, little is known about the molecular mechanism of …

[HTML][HTML] Risk of sperm disorders and impaired fertility in frozen–thawed bull semen: a genome-wide association study

NV Dementieva, AP Dysin, YS Shcherbakov… - Animals, 2024 - mdpi.com
Simple Summary This study tackles the genetic aspects of the risk of sperm damage and
related impaired fertility when handling frozen–thawed bull semen for artificial insemination …

Tomato spotted wilt orthotospovirus shifts sex ratio toward males in the western flower thrips, Frankliniella occidentalis, by down‐regulating a FSCB‐like gene

M Tao, Y Wan, X Zheng, K Qian… - Pest Management …, 2022 - Wiley Online Library
BACKGROUND Plant viruses can facilitate their transmission by modulating the sex ratios of
their insect vectors. Previously, we found that exposure to tomato spotted wilt …

[HTML][HTML] Does the pre-ovulatory pig oviduct rule sperm capacitation in vivo mediating transcriptomics of Catsper channels?

CA Martinez, M Alvarez-Rodriguez, D Wright… - International Journal of …, 2020 - mdpi.com
Spermatozoa need to conduct a series of biochemical changes termed capacitation in order
to fertilize. In vivo, capacitation is sequentially achieved during sperm transport and …

[HTML][HTML] FSCB phosphorylation regulates mouse spermatozoa capacitation through suppressing SUMOylation of ROPN1/ROPN1L

X Zhang, M Chen, R Yu, B Liu, Z Tian… - American Journal of …, 2016 - ncbi.nlm.nih.gov
Fibrous sheath CABYR binding protein (FSCB) is regulated by protein kinase A (PKA)-
mediated tyrosine phosphorylation in the spermatozoa capacitation. Recently, we showed …