Polymeric vesicles in biomedical applications

RP Brinkhuis, FPJT Rutjes, JCM van Hest - Polymer Chemistry, 2011 - pubs.rsc.org
Polymeric vesicles, or polymersomes, are nano-to micrometre sized polymeric capsules with
a bilayered membrane. Applications of these vesicles are foreseen in nanomedicine, in vivo …

Theoretical modeling and simulations of self-assembly of copolymers in solution

Q Zhang, J Lin, L Wang, Z Xu - Progress in Polymer Science, 2017 - Elsevier
Self-assembly of copolymers in solution is a promising way to prepare novel materials. An
accurate control over the self-assembly of copolymers in solution requires a profound …

Polymersome stomatocytes: controlled shape transformation in polymer vesicles

KT Kim, J Zhu, SA Meeuwissen… - Journal of the …, 2010 - ACS Publications
We report here a controllable shape transformation of polymer vesicles (polymersomes)
constructed from block copolymers of which the hydrophobic part is a high-molecular-weight …

A coarse-grained red blood cell membrane model to study stomatocyte-discocyte-echinocyte morphologies

NM Geekiyanage, MA Balanant, E Sauret, S Saha… - PLoS …, 2019 - journals.plos.org
An improved red blood cell (RBC) membrane model is developed based on the bilayer
coupling model (BCM) to accurately predict the complete sequence of stomatocyte-discocyte …

Polymersome shape transformation at the nanoscale

R Salva, JF Le Meins, O Sandre, A Brûlet, M Schmutz… - ACS …, 2013 - ACS Publications
Polymer vesicles, also named polymersomes, are valuable candidates for drug delivery and
micro-or nanoreactor applications. As far as drug delivery is concerned, the shape of the …

Dissipative particle dynamics studies on microstructure of pH-sensitive micelles for sustained drug delivery

XD Guo, LJ Zhang, ZM Wu, Y Qian - Macromolecules, 2010 - ACS Publications
Dissipative particle dynamics simulations were performed to study the microstructures of
doxorubicin (DOX) loaded/blank micelles self-assembled from cholesterol conjugated …

Polymersomes in Drug Delivery─ From Experiment to Computational Modeling

Q Xu, Y Wang, Y Zheng, Y Zhu, Z Li, Y Liu… - …, 2023 - ACS Publications
Polymersomes, composed of amphiphilic block copolymers, are self-assembled vesicles
that have gained attention as potential drug delivery systems due to their good …

Phase diagrams of block copolymer melts by dissipative particle dynamics simulations

AA Gavrilov, YV Kudryavtsev… - The Journal of chemical …, 2013 - pubs.aip.org
Phase diagrams for monodisperse and polydisperse diblock copolymer melts and a random
multiblock copolymer melt are constructed using dissipative particle dynamics simulations. A …

Polymeric supramolecular systems for drug delivery

HJ Yoon, WD Jang - Journal of Materials Chemistry, 2010 - pubs.rsc.org
Recent advances in supramolecular chemistry have had significant influence on the
biomedical applications of materials chemistry. Supramolecular systems are based on weak …

Simulations of morphology control of self‐assembled amphiphilic surfactants

Q Zhu, DR Tree - Journal of Polymer Science, 2023 - Wiley Online Library
One of the grand challenges of amphiphilic self‐assembly is the design of ordered structures
whose morphology or shape can be explicitly and dynamically controlled by adjusting the …