[HTML][HTML] Role of hydrogen sulfide in the regulation of lipid metabolism: Implications on cardiovascular health

F Lorenzo, P Eugenia, C Vincenzo, T Lara - Life sciences, 2024 - Elsevier
Abstract The World Health Organization (WHO) defines obesity as an urgency for health and
a social emergency. Today around 39% of people is overweight, of these over 13% is …

[HTML][HTML] Dietary pattern and hepatic lipid metabolism

P Zou, L Wang - Liver Research, 2023 - Elsevier
The liver is the leading site for lipid metabolism, involving not only fatty acid beta-oxidation
but also de novo synthesis of endogenous triglycerides and ketogenesis. The liver maintains …

Advances in the study of vascular related protective effect of garlic (Allium sativum) extract and compounds

M Lu, J Pan, Y Hu, L Ding, Y Li, X Cui, M Zhang… - The Journal of …, 2023 - Elsevier
Garlic (Allium sativum) is a functional food containing multiple bioactive compounds that find
widespread applications in culinary and medicinal practices. It consists of multiple chemical …

Krüppel-like factor 15 in liver diseases: Insights into metabolic reprogramming

H Chen, LL Li, Y Du - Frontiers in Pharmacology, 2023 - frontiersin.org
Liver diseases, characterized by metabolic disorder, have become a global public health
problem with high morbidity and mortality. Krüppel-like factor 15 (KLF15) is a zinc-finger …

Diallyl trisulfide regulates PGK1/Nrf2 expression and reduces inflammation to alleviate neurological damage in mice after traumatic brain injury

Y Chen, J Pang, Y Chen, Y Liang, Z Zhang, Z Wang - Brain Research, 2024 - Elsevier
Background Diallyl trisulfide (DATS) has a direct antioxidant capacity and emerges as a
promising neuroprotective agent. This study was designed to investigate the role of DATS in …

KIO 3-catalyzed selective oxidation of thiols to disulfides in water under ambient conditions

JRL Sousa, MS Franco, LD Mendes… - Organic & …, 2024 - pubs.rsc.org
Herein, we report a KIO3-catalyzed oxidative coupling of thiols to their corresponding
disulfides in water, in a short time and at ambient temperature. The reaction has a broad …

KLF15 transcriptionally activates LINC00689 to inhibit colorectal cancer development

Y Cao, J Li, G Zhang, H Fang, Y Du, Y Liang - Communications Biology, 2024 - nature.com
Colorectal cancer is a grievous health concern, we have proved long non-coding RNA
LINC00689 is considered as a potential diagnosis biomarker for colorectal cancer, and it is …

Aptamer-functionalized liposome delivery system targeting adipose for hypereffective obesity therapy

Y Song, Y Hu, R Gao, Q Chang, X He, G Pang… - Journal of Drug Delivery …, 2024 - Elsevier
Preparation of DNA micro/nanostructures with high accuracy, high effectiveness, and low
toxicity remains a challenge in the fields of biotargeting drugs and therapeutics. Aptamer …

Aptamer-functionalized-nanoflower loading allicin ameliorates obesity through regulating adipose tissue energy expenditure

T Wang, Y Yu, R Gao, X Chen, W Xu, K Huang… - Journal of Drug Delivery …, 2024 - Elsevier
The aptamer-functionalized nanoflower-allicin delivery system (NFA) constructed with the
adipo-8 aptamer can load allicin and target adipose tissue. This delivery strategy is …

Effects of allicin on human Simpson-Golabi-Behmel syndrome cells in mediating browning phenotype

U Ali, M Wabitsch, D Tews, M Colitti - Frontiers in Endocrinology, 2023 - frontiersin.org
Introduction Obesity is a major health problem because it is associated with increased risk of
cardiovascular disease, diabetes, hypertension, and some cancers. Strategies to prevent or …