CryoEM reveals how the small molecule EGCG binds to Alzheimer's brain-derived tau fibrils and initiates fibril disaggregation

PM Seidler, DR Boyer, MR Sawaya, P Ge, WS Shin… - bioRxiv, 2020 - biorxiv.org
EGCG, the most abundant favanol in green tea, is one of the few natural compounds known
to inhibit amyloid fibril formation of proteins associated with neurodegeneration, and to …