Evidences for adult hippocampal neurogenesis in humans

EP Moreno-Jiménez, J Terreros-Roncal… - Journal of …, 2021 - Soc Neuroscience
The rodent hippocampus generates new neurons throughout life. This process, named adult
hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the …

Adult hippocampal neurogenesis in aging and Alzheimer's disease

KR Babcock, JS Page, JR Fallon, AE Webb - Stem cell reports, 2021 - cell.com
Cognitive deficits associated with Alzheimer's disease (AD) severely impact daily life for the
millions of affected individuals. Progressive memory impairment in AD patients is associated …

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease

EP Moreno-Jiménez, M Flor-García… - Nature medicine, 2019 - nature.com
The hippocampus is one of the most affected areas in Alzheimer's disease (AD) 1. Moreover,
this structure hosts one of the most unique phenomena of the adult mammalian brain …

Environmental enrichment, new neurons and the neurobiology of individuality

G Kempermann - Nature Reviews Neuroscience, 2019 - nature.com
Abstract 'Enriched environments' are a key experimental paradigm to decipher how
interactions between genes and environment change the structure and function of the brain …

Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain

MP Jurkowski, L Bettio, E K. Woo, A Patten… - Frontiers in cellular …, 2020 - frontiersin.org
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Neurogenesis in the adult hippocampus

G Kempermann, H Song… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the
most attention, because it is involved in higher cognitive function, most notably memory …

Neural basis of major depressive disorder: Beyond monoamine hypothesis

S Boku, S Nakagawa, H Toda… - Psychiatry and clinical …, 2018 - Wiley Online Library
The monoamine hypothesis has been accepted as the most common hypothesis of major
depressive disorder (MDD) for a long period because of its simplicity and understandability …

Positive controls in adults and children support that very few, if any, new neurons are born in the adult human hippocampus

SF Sorrells, MF Paredes, Z Zhang, G Kang… - Journal of …, 2021 - Soc Neuroscience
Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies
identified the adult neural stem cells and found important links between adult neurogenesis …

[HTML][HTML] Depression and adult neurogenesis: Positive effects of the antidepressant fluoxetine and of physical exercise

L Micheli, M Ceccarelli, G D'Andrea, F Tirone - Brain research bulletin, 2018 - Elsevier
Of wide interest for health is the relation existing between depression, a very common
psychological illness, accompanied by anxiety and reduced ability to concentrate, and adult …

Distinct contribution of adult-born hippocampal granule cells to context encoding

NB Danielson, P Kaifosh, JD Zaremba, M Lovett-Barron… - Neuron, 2016 - cell.com
Adult-born granule cells (abGCs) have been implicated in cognition and mood; however, it
remains unknown how these cells behave in vivo. Here, we have used two-photon calcium …