[HTML][HTML] AI-based monitoring of retinal fluid in disease activity and under therapy

U Schmidt-Erfurth, GS Reiter, S Riedl… - Progress in retinal and …, 2022 - Elsevier
Retinal fluid as the major biomarker in exudative macular disease is accurately visualized by
high-resolution three-dimensional optical coherence tomography (OCT), which is used …

OCT Biomarkers in Neovascular Age‐Related Macular Degeneration: A Narrative Review

C Metrangolo, S Donati, M Mazzola… - Journal of …, 2021 - Wiley Online Library
Age‐related macular degeneration (AMD) is the leading cause of legal blindness in elderly
people. Neovascular AMD (nAMD) is responsible for the majority of cases of severe visual …

[HTML][HTML] The effect of pegcetacoplan treatment on photoreceptor maintenance in geographic atrophy monitored by artificial intelligence–based OCT analysis

S Riedl, WD Vogl, J Mai, GS Reiter, D Lachinov… - Ophthalmology …, 2022 - Elsevier
Purpose To investigate the therapeutic effect of intravitreal pegcetacoplan on the inhibition
of photoreceptor (PR) loss and thinning in geographic atrophy (GA) on conventional spectral …

[HTML][HTML] Role of deep learning–quantified hyperreflective foci for the prediction of geographic atrophy progression

U Schmidt-Erfurth, H Bogunovic, C Grechenig… - American journal of …, 2020 - Elsevier
Purpose To quantitatively measure hyperreflective foci (HRF) during the progression of
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) using deep …

Analysis of fluid volume and its impact on visual acuity in the fluid study as quantified with deep learning

GS Reiter, C Grechenig, WD Vogl, RH Guymer… - Retina, 2021 - journals.lww.com
Purpose: To investigate quantitative differences in fluid volumes between subretinal fluid
(SRF)–tolerant and SRF-intolerant treat-and-extend regimens for neovascular age-related …

[HTML][HTML] Impact of fluid compartments on functional outcomes for patients with neovascular age-related macular degeneration: a systematic literature review

V Chaudhary, F Matonti, J Zarranz-Ventura… - Retina, 2022 - journals.lww.com
Purpose: Understanding the impact of fluid in different retinal compartments is critical to
developing treatment paradigms that optimize visual acuity and reduce treatment burden in …

[HTML][HTML] Predicting treat-and-extend outcomes and treatment intervals in neovascular age-related macular degeneration from retinal optical coherence tomography …

H Bogunović, V Mares, GS Reiter… - Frontiers in …, 2022 - frontiersin.org
Purpose: To predict visual outcomes and treatment needs in a treat & extend (T&E) regimen
in neovascular age-related macular degeneration (nAMD) using a machine learning model …

[HTML][HTML] Non-invasive hybrid ultrasound stimulation of visual cortex in vivo

C Gong, R Li, G Lu, J Ji, Y Zeng, J Chen, C Chang… - Bioengineering, 2023 - mdpi.com
The optic nerve is the second cranial nerve (CN II) that connects and transmits visual
information between the retina and the brain. Severe damage to the optic nerve often leads …

Retinal neurodegeneration in age-related macular degeneration

C Barresi, J Chhablani, R Dolz-Marco… - European Journal …, 2024 - journals.sagepub.com
Age-related macular degeneration (AMD) is a complex and multifactorial disease
characterized by the damage of the unit comprised of the photoreceptors, retinal pigment …

[HTML][HTML] Longitudinal assessment of ellipsoid zone integrity, subretinal hyperreflective material, and subretinal pigment epithelium disease in neovascular age-related …

JP Ehlers, R Zahid, PK Kaiser, JS Heier, DM Brown… - Ophthalmology …, 2021 - Elsevier
Purpose To assess longitudinally the effect of anti–vascular endothelial growth factor
(VEGF) treatment on ellipsoid zone (EZ) integrity, subretinal hyperreflective material …