Electromagnetic fields affect transcript levels of apoptosis‐related genes in embryonic stem cell‐derived neural progenitor cells

T Nikolova, J Czyz, A Rolletschek… - The FASEB …, 2005 - Wiley Online Library
Mouse embryonic stem (ES) cells were used as an experimental model to study the effects
of electromagnetic fields (EMF). ES‐derived nestin‐positive neural progenitor cells were …

Interpreting crosstalk between TNF-α and NGF: potential implications for disease

Y Takei, R Laskey - Trends in Molecular Medicine, 2008 - cell.com
Tumour necrosis factor-α (TNF-α) is a proinflammatory cytokine, whereas nerve growth
factor (NGF) is a neurotrophin that can promote neural cell survival, differentiation and …

Possible association between isotretinoin and inflammatory bowel disease

D Reddy, CA Siegel, BE Sands… - Official journal of the …, 2006 - journals.lww.com
OBJECTIVES The Physician's Desk Reference lists inflammatory bowel disease (IBD) as a
possible adverse event associated with the use of isotretinoin, a popular acne prescription …

Coupled global and targeted proteomics of human embryonic stem cells during induced differentiation

AK Yocum, TE Gratsch, N Leff, JR Strahler… - Molecular & Cellular …, 2008 - ASBMB
Elucidating the complex combinations of growth factors and signaling molecules that
maintain pluripotency or, alternatively, promote the controlled differentiation of human …

Temporal analysis of neural differentiation using quantitative proteomics

R Chaerkady, CL Kerr, A Marimuthu… - Journal of proteome …, 2009 - ACS Publications
The ability to derive neural progenitors, differentiated neurons and glial cells from human
embryonic stem cells (hESCs) with high efficiency holds promise for a number of clinical …

Interleukin-18 and macrophage migration inhibitory factor are associated with increased carotid intima–media thickening

VA Korshunov, TA Nikonenko, VA Tkachuk… - … , and vascular biology, 2006 - Am Heart Assoc
Objective—Carotid intima–media thickening (IMT) is a form of vascular remodeling that has
a strong genetic component. Recently, we discovered that in response to decreased carotid …

Tumor necrosis factor α regulates responses to nerve growth factor, promoting neural cell survival but suppressing differentiation of neuroblastoma cells

Y Takei, R Laskey - Molecular biology of the cell, 2008 - Am Soc Cell Biol
Although nerve growth factor (NGF) promotes survival of neurons, tumor necrosis factor α
(TNF-α) contributes to cell death triggered by NGF depletion, through TNF-α receptor (TNFR) …

Effects of Strain and Treatment with Inhaled All-Trans-Retinoic Acid on Cigarette Smoke-Induced Pulmonary Emphysema in Mice

TH March, LE Bowen, GL Finch, KJ Nikula… - COPD: Journal of …, 2005 - Taylor & Francis
Models of emphysema produced by exposing animals to cigarette smoke (CS) have
potential for use in testing treatments of this disease. To better characterize development of …

Comparison of Matrigel™ and gelatin substrata for feeder-free culture of undifferentiated mouse embryonic stem cells for toxicity testing

AR Greenlee, TA Kronenwetter-Koepel, SJ Kaiser… - Toxicology in vitro, 2005 - Elsevier
Murine embryonic stem (mES) cells have been used to evaluate cytotoxicity and
developmental injury following exposure to embryotoxic agents. However, maintaining a …

A student team in a University of Michigan biomedical engineering design course constructs a microfluidic bioreactor for studies of zebrafish development

Y Shen, D Li, A Al-Shoaibi, T Bersano-Begey, H Chen… - Zebrafish, 2009 - liebertpub.com
The zebrafish is a valuable model for teaching developmental, molecular, and cell biology;
aquatic sciences; comparative anatomy; physiology; and genetics. Here we demonstrate …