Overview and update on extracellular vesicles: considerations on exosomes and their application in modern medicine
MA Di Bella - Biology, 2022 - mdpi.com
Simple Summary Exosomes are a subpopulation of extracellular vesicles, nanosized
particles, lipid bilayer-enclosed, naturally secreted from cells after the fusion of intracellular …
particles, lipid bilayer-enclosed, naturally secreted from cells after the fusion of intracellular …
Exosomes and breast cancer drug resistance
Drug resistance is a daunting challenge in the treatment of breast cancer (BC). Exosomes,
as intercellular communicative vectors in the tumor microenvironment, play an important role …
as intercellular communicative vectors in the tumor microenvironment, play an important role …
Pathways to endocrine therapy resistance in breast cancer
Breast cancers with positive expression of Estrogen Receptor (ER+) are treated with anti-
hormone/endocrine therapy which targets the activity of the receptor, the half-life of the …
hormone/endocrine therapy which targets the activity of the receptor, the half-life of the …
Molecular mechanisms of endocrine resistance in estrogen-receptor-positive breast cancer
EB Belachew, DT Sewasew - Frontiers in endocrinology, 2021 - frontiersin.org
The estrogen receptor is a vital receptor for therapeutic targets in estrogen receptor-positive
breast cancer. The main strategy for the treatment of estrogen receptor-positive breast …
breast cancer. The main strategy for the treatment of estrogen receptor-positive breast …
Exosomes as drug delivery vehicle and contributor of resistance to anticancer drugs
Exosomes are small membranous vesicles implicated in intercellular signalling. Through
their uncanny ability to carry and deliver donor cellular cargo (biomolecules) to target cells …
their uncanny ability to carry and deliver donor cellular cargo (biomolecules) to target cells …
The emerging roles of exosomes in anti-cancer drug resistance and tumor progression: An insight towards tumor-microenvironment interaction
The tumor microenvironment (TME) is a complex network of cellular organization consisting
of fibroblasts, adipocytes, pericytes, immune cells endothelial cells, and extracellular matrix …
of fibroblasts, adipocytes, pericytes, immune cells endothelial cells, and extracellular matrix …
The role of exosomes in human carcinogenesis and cancer therapy—Recent findings from molecular and clinical research
K Stefańska, M Józkowiak, A Angelova Volponi… - Cells, 2023 - mdpi.com
Exosomes are biological nanoscale spherical lipid bilayer vesicles, 40–160 nm in diameter,
produced by most mammalian cells in both physiological and pathological conditions …
produced by most mammalian cells in both physiological and pathological conditions …
[HTML][HTML] Exosomes mediated transfer of Circ_UBE2D2 enhances the resistance of breast cancer to tamoxifen by binding to MiR-200a-3p
K Hu, X Liu, Y Li, Q Li, Y Xu, W Zeng… - … medical journal of …, 2020 - ncbi.nlm.nih.gov
Background Circular RNA UBE2D2 (circ_UBE2D2) has been found to be involved in the
progression of breast cancer. Exosomes are critical mediators of intercellular …
progression of breast cancer. Exosomes are critical mediators of intercellular …
Metformin increases exosome biogenesis and secretion in U87 MG human glioblastoma cells: a possible mechanism of therapeutic resistance
Background Glioblastoma multiforme (GBM) is the most common and aggressive brain
tumor. Metformin, an anti-diabetic drug, can suppress tumor cells. Exosomes from GBM cells …
tumor. Metformin, an anti-diabetic drug, can suppress tumor cells. Exosomes from GBM cells …
[HTML][HTML] Landscape of extracellular vesicles in the tumour microenvironment: Interactions with stromal cells and with non-cell components, and impacts on metabolic …
Extracellular vesicles (EVs) are increasingly recognised as a pivotal player in cell-cell
communication, an attribute of EVs that derives from their ability to transport bioactive …
communication, an attribute of EVs that derives from their ability to transport bioactive …