Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Cryptococcal meningitis is a leading cause of morbidity and mortality globally, especially in
people with advanced HIV disease. Cryptococcal meningitis is responsible for nearly 20% of …

Eumycetoma is a chronic subcutaneous neglected tropical disease that can be caused by
more than 40 different fungal causative agents. The most common causative agents produce …

There is a consensus that the antifungal repertoire for the treatment of cryptococcal
infections is limited. Standard treatment involves the administration of an antifungal drug …

Fungal infections are a major public health problem resulting from the lack of public policies
addressing these diseases, toxic and/or expensive therapeutic tools, scarce diagnostic tests …

Introduction The three fungal skin neglected tropical diseases (NTD)–mycetoma,
chromoblastomycosis and sporotrichosis–currently lack prioritization and support to …

Chromoblastomycosis (CBM) is a neglected human implantation mycosis caused by several
dematiaceous fungal species. Currently available therapy is usually associated with …

In recent years, there has been a considerable rise in the production of novel metabolites
derived from fungi compared to the ones originating from bacteria. These organic …

As the existing therapeutic modalities for the treatment of cryptococcal meningitis (CM) have
suboptimal efficacy, repurposing existing drugs for the treatment of CM is of great interest …

Benzimidazoles, one of the nitrogen heterocycles, possess pharmaceutical and biological
potential. This heterocycle has been known for pharmacological activities such as …