Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …

Integrins are heterodimeric cell surface receptors ensuring the mechanical connection
between cells and the extracellular matrix. In addition to the anchorage of cells to the …

The adhesive interactions of cells with their environment through the integrin family of
transmembrane receptors have key roles in regulating multiple aspects of cellular …

Basement membranes are widely distributed extracellular matrices that coat the basal
aspect of epithelial and endothelial cells and surround muscle, fat, and Schwann cells …

We report the identification of rat and human cDNAs for a type 1 membrane protein that
contains a novel six-cysteine immunoglobulin-like domain and a mucin domain; it is named …

To provide a stable environmental barrier, the epidermis requires an integrated network of
cytoskeletal elements and cellular junctions. Nevertheless, the epidermis ranks among the …

Cell-surface proteins of the tetraspanin family are small, and often hidden by a canopy of tall
glycoprotein neighbours in the cell membrane. Consequently, tetraspanins have been …

Laminins are a large family of conserved, multidomain trimeric basement membrane
proteins that contribute to the structure of extracellular matrix and influence the behavior of …

The laminins are a family of glycoproteins that provide an integral part of the structural
scaffolding of basement membranes in almost every animal tissue. Each laminin is a …

At the surface of the skin, the epidermis serves as the armour for the body. Scientists are
now closer than ever to understanding how the epidermis accomplishes this extraordinary …