Small-molecule two-photon probes for bioimaging applications

HM Kim, BR Cho - Chemical reviews, 2015 - ACS Publications
Small-molecule fluorescent probes are attractive and versatile materials for studying
biological systems.(1-6) They can be easily loaded into cells and rapidly detect biological …

Design strategies for water-soluble small molecular chromogenic and fluorogenic probes

X Li, X Gao, W Shi, H Ma - Chemical reviews, 2014 - ACS Publications
Chromogenic and fluorogenic probes may be described as the reagents that can interact
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …

Metal coordination in photoluminescent sensing

Z Liu, W He, Z Guo - Chemical Society Reviews, 2013 - pubs.rsc.org
Coordination chemistry plays an essential role in the design of photoluminescent probes for
metal ions. Metal coordination to organic dyes induces distinct optical responses which …

Two‐photon absorption and the design of two‐photon dyes

M Pawlicki, HA Collins, RG Denning… - Angewandte Chemie …, 2009 - Wiley Online Library
Two photons are better than one: This principle applies to a wide range of applications,
ranging from engineering to physiology. Recent advances in our understanding of the …

[HTML][HTML] Zinc homeostasis and signaling in health and diseases: Zinc signaling

T Fukada, S Yamasaki, K Nishida, M Murakami… - JBIC Journal of …, 2011 - Springer
The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal
Zn homeostasis causes a variety of health problems that include growth retardation …

Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent Sensor

Z Xu, KH Baek, HN Kim, J Cui, X Qian… - Journal of the …, 2010 - ACS Publications
It is still a significant challenge to develop a Zn2+-selective fluorescent sensor with the ability
to exclude the interference of some heavy and transition metal (HTM) ions such as Fe2+ …

In situ imaging of metals in cells and tissues

R McRae, P Bagchi, S Sumalekshmy… - Chemical …, 2009 - ACS Publications
Approximately one third of the human proteome contains metal cations, either in the form of
cofactors with catalytic functions or as structural support elements. 1, 2 To guarantee a …

Benzimidazole-based ratiometric two-photon fluorescent probes for acidic pH in live cells and tissues

HJ Kim, CH Heo, HM Kim - Journal of the American Chemical …, 2013 - ACS Publications
Many aspects of cell metabolism are controlled by acidic pH. We report a new family of small
molecule and ratiometric two photon (TP) probes derived from benzimidazole (BH1–3 and …

Molecular and genetic features of zinc transporters in physiology and pathogenesis

T Fukada, T Kambe - Metallomics, 2011 - academic.oup.com
Zinc (Zn) is a vital element. It plays indispensable roles in multifarious cellular processes,
affecting the expression and activity of a variety of molecules, including transcription factors …

Visible Light Excitable Zn2+ Fluorescent Sensor Derived from an Intramolecular Charge Transfer Fluorophore and Its in Vitro and in Vivo Application

F Qian, C Zhang, Y Zhang, W He, X Gao… - Journal of the …, 2009 - ACS Publications
The UV-and sensor-induced interferences to living systems pose a barrier for in vivo Zn2+
imaging. In this work, an intramolecular charge transfer (ICT) fluorophore of smaller aromatic …