Pathophysiology of skin resident memory T cells

Y Tokura, P Phadungsaksawasdi, K Kurihara… - Frontiers in …, 2021 - frontiersin.org
Tissue resident memory T (TRM) cells reside in peripheral, non-lymphoid tissues such as
the skin, where they act as alarm-sensor cells or cytotoxic cells. Physiologically, skin TRM …

[HTML][HTML] Molecular pathogenesis of Cutaneous T cell Lymphoma: Role of chemokines, cytokines, and dysregulated signaling pathways

K Patil, S Kuttikrishnan, AQ Khan, F Ahmad… - Seminars in Cancer …, 2022 - Elsevier
Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of lymphoproliferative
neoplasms that exhibit a wide spectrum of immune-phenotypical, clinical, and …

Treatment and survival among 1594 patients with ATL

H Katsuya, K Ishitsuka, A Utsunomiya… - Blood, The Journal …, 2015 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is a malignancy of mature T lymphocytes caused by
human T-lymphotropic virus type I. Intensive combination chemotherapy and allogeneic …

CCR4 as a therapeutic target for cancer immunotherapy

O Yoshie - Cancers, 2021 - mdpi.com
Simple Summary CCR4 is a chemokine receptor selectively expressed on normal T cell
subsets such as type 2 helper T cells, skin-homing T cells and regulatory T cells, and on skin …

New therapies and immunological findings in cutaneous T-cell lymphoma

K Fujii - Frontiers in oncology, 2018 - frontiersin.org
Primary cutaneous lymphomas comprise a group of lymphatic malignancies that occur
primarily in the skin. They represent the second most common form of extranodal non …

Cutaneous B-cell lymphoma

A Goyal, RE LeBlanc, JB Carter - Hematology/Oncology …, 2019 - hemonc.theclinics.com
Primary cutaneous B-cell lymphomas (pcBCLs) are non-Hodgkin B-cell lymphomas
originating in the skin without evidence of extracutaneous disease at presentation. 1 In the …

Cutaneous metastasis

JD Strickley, AB Jenson… - Hematology/Oncology …, 2019 - hemonc.theclinics.com
Cutaneous metastasis accounts for only 2% of all skin cancers, 1 but incidence is increasing
due to improved survival of patients with cancer as a whole. 2 The importance of prompt …

Antitumor effects of chloroquine/hydroxychloroquine mediated by inhibition of the NF-κB signaling pathway through abrogation of autophagic p47 degradation in adult …

YR Fauzi, S Nakahata, S Chilmi, T Ichikawa… - PLoS …, 2021 - journals.plos.org
Adult T-cell leukemia/lymphoma (ATLL) originates from human T-cell leukemia virus type 1
(HTLV-1) infection due to the activation of the nuclear factor-κB (NF-κB) signaling pathway to …

STING signaling and skin cancers

S Sato, Y Sawada, M Nakamura - Cancers, 2021 - mdpi.com
Simple Summary Stimulator of interferon genes (STING) is currently recognized as a driver
for anti-tumor immunity against various malignancies and is expected to enhance the anti …

Cutaneous manifestations of adult T-cell leukemia/lymphoma

D Miyashiro, JA Sanches - Seminars in Diagnostic Pathology, 2020 - Elsevier
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive peripheral T-cell lymphoma
caused by the human T-lymphotropic virus type-1 (HTLV-1). The skin is affected in …