Simple Summary A brief description of the methodologies to simulate ionizing radiation
transport in biologically relevant matter is presented. Emphasis is given to the physical …

Purpose The scientific community shows great interest in the study of DNA damage
induction, DNA damage repair, and the biological effects on cells and cellular systems after …

The lack of molecular-level understanding for the electronic excitation response of DNA to
charged particle radiation, such as high-energy protons, remains a fundamental scientific …

This paper demonstrates the impact of the pre-chemical stage, especially the dissociation
scheme and the associated probabilities, on water radiolysis simulation using the Geant4 …

Abstract Purpose In radiation physics, Monte Carlo radiation transport simulations are
powerful tools to evaluate the cellular responses after irradiation. When investigating such …

Radioligand therapy is an emerging and effective treatment option for various types of
malignancies, but may be intricately linked to hematological side effects such as anemia …

This topical review summarizes underlying concepts of nanodosimetry. It describes the
development and current status of nanodosimetric detector technology. It also gives an …

Simple Summary An increasing number of cancer patients are treated with proton therapy.
Nevertheless, there are still open questions that require preclinical studies, for example …

Simple Summary DNA damage caused by ionizing radiation in a human fibroblast cell
evaluated by the Geant4-DNA Monte Carlo toolkit is presented. A validation study using a …

Abstract Purpose: Track structure Monte Carlo (MC) codes have achieved successful
outcomes in the quantitative investigation of radiation-induced initial DNA damage. The aim …