Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application
T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …
Stability prediction of canonical and non-canonical structures of nucleic acids in various molecular environments and cells
S Takahashi, N Sugimoto - Chemical Society Reviews, 2020 - pubs.rsc.org
Nucleic acids (DNA and RNA) dynamically fold and unfold to exert their functions in cells.
These folding and unfolding behaviours are also the basis for various technical applications …
These folding and unfolding behaviours are also the basis for various technical applications …
Chemical regulation of DNA i‐motifs for nanobiotechnology and therapeutics
DNA sequences rich in cytosine have the propensity, under acidic pH, to fold into four‐
stranded intercalated DNA structures called i‐motifs. Recent studies have provided …
stranded intercalated DNA structures called i‐motifs. Recent studies have provided …
[HTML][HTML] In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells
P Víšková, E Ištvánková, J Ryneš, Š Džatko… - Nature …, 2024 - nature.com
I-Motifs (iM) are non-canonical DNA structures potentially forming in the accessible, single-
stranded, cytosine-rich genomic regions with regulatory roles. Chromatin, protein …
stranded, cytosine-rich genomic regions with regulatory roles. Chromatin, protein …
Systematic investigation of sequence requirements for DNA i-motif formation
P Školáková, D Renčiuk, J Palacký… - Nucleic Acids …, 2019 - academic.oup.com
The formation of intercalated motifs (iMs)—secondary DNA structures based on
hemiprotonated C. C+ pairs in suitable cytosine-rich DNA sequences, is reflected by typical …
hemiprotonated C. C+ pairs in suitable cytosine-rich DNA sequences, is reflected by typical …
DNA i-motif formation at neutral pH is driven by kinetic partitioning
P Školáková, M Gajarský, J Palacký… - Nucleic Acids …, 2023 - academic.oup.com
Cytosine-rich DNA regions can form four-stranded structures based on hemi-protonated C.
C+ pairs, called i-motifs (iMs). Using CD, UV absorption, NMR spectroscopy, and DSC …
C+ pairs, called i-motifs (iMs). Using CD, UV absorption, NMR spectroscopy, and DSC …
Effects of Sequence and Base Composition on the CD and TDS Profiles of i‐DNA
The i‐motif DNA, also known as i‐DNA, is a non‐canonical DNA secondary structure formed
by cytosine‐rich sequences, consisting of two intercalated parallel‐stranded duplexes held …
by cytosine‐rich sequences, consisting of two intercalated parallel‐stranded duplexes held …
AC-motif: a DNA motif containing adenine and cytosine repeat plays a role in gene regulation
JH Hur, CY Kang, S Lee, N Parveen, J Yu… - Nucleic Acids …, 2021 - academic.oup.com
I-motif or C4 is a four-stranded DNA structure with a protonated cytosine: cytosine base pair
(C+: C) found in cytosine-rich sequences. We have found that oligodeoxynucleotides …
(C+: C) found in cytosine-rich sequences. We have found that oligodeoxynucleotides …
Single-molecule analysis of i-motif within self-assembled DNA duplexes and nanocircles
A Megalathan, BD Cox, PD Wilkerson… - Nucleic Acids …, 2019 - academic.oup.com
The cytosine (C)-rich sequences that can fold into tetraplex structures known as i-motif are
prevalent in genomic DNA. Recent studies of i-motif–forming sequences have shown …
prevalent in genomic DNA. Recent studies of i-motif–forming sequences have shown …
[HTML][HTML] Tricky topology: persistence of folded human telomeric i-motif DNA at ambient temperature and neutral pH
MAS Abdelhamid, ZAE Waller - Frontiers in Chemistry, 2020 - frontiersin.org
i-Motifs are four-stranded DNA structures formed from sequences rich in cytosine, held
together by hemi-protonated cytosine-cytosine base pairs. These structures have been …
together by hemi-protonated cytosine-cytosine base pairs. These structures have been …