[HTML][HTML] Roles of melatonin in the field of reproductive medicine

W Yong, H Ma, M Na, T Gao, Y Zhang, L Hao… - Biomedicine & …, 2021 - Elsevier
Melatonin, mostly released by the pineal gland, is a circadian rhythm-regulated and
multifunctional hormone. Great advances in melatonin research have been made, including …

The role of oxidative stress and natural antioxidants in ovarian aging

L Yang, Y Chen, Y Liu, Y Xing, C Miao… - Frontiers in …, 2021 - frontiersin.org
The ovarian system comprises vital organs in females and is of great significance for the
maintenance of reproductive potential and endocrine stability. Although complex …

Advances in oocyte maturation in vivo and in vitro in mammals

Y Jiang, Y He, X Pan, P Wang, X Yuan… - International journal of …, 2023 - mdpi.com
The quality and maturation of an oocyte not only play decisive roles in fertilization and
embryo success, but also have long-term impacts on the later growth and development of …

The process of ovarian aging: it is not just about oocytes and granulosa cells

A Camaioni, MA Ucci, L Campagnolo… - Journal of assisted …, 2022 - Springer
Ovarian age is classically considered the main cause of female reproductive infertility. In
women, the process proceeds as an ongoing decline in the primordial follicle stockpile and it …

Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development

BR Silva, JRV Silva - Animal reproduction science, 2023 - Elsevier
In vitro follicle growth and oocyte maturation still has a series of limitations, since not all
oocytes matured in vitro have the potential to develop in viable embryos. One of the factors …

Oxidative stress and human ovarian response—from somatic ovarian cells to oocytes damage: a clinical comprehensive narrative review

V Immediata, C Ronchetti, D Spadaro, F Cirillo… - Antioxidants, 2022 - mdpi.com
Basic scientific research on human reproduction and oxidative damage has been
extensively performed; however, a more clinical view is still lacking. As a result, exhaustive …

Positive effects of amphiregulin on human oocyte maturation and its molecular drivers in patients with polycystic ovary syndrome

N Akin, AH Le, UDT Ha, S Romero… - Human …, 2022 - academic.oup.com
STUDY QUESTION Does use of medium containing amphiregulin improve meiotic
maturation efficiency in oocytes of women with polycystic ovary syndrome (PCOS) …

Potential of nobiletin against Alzheimer's disease through inhibiting neuroinflammation

W Chai, J Zhang, Z Xiang, H Zhang, Z Mei, H Nie… - Metabolic brain …, 2022 - Springer
Objective This study aimed to explore the mechanism of Nobiletin attenuating Alzheimer's
disease (AD) by inhibiting neuroinflammation. Methods The expression of inflammatory …

Impact of NAD+ metabolism on ovarian aging

J Liang, F Huang, Z Song, R Tang, P Zhang, R Chen - Immunity & Ageing, 2023 - Springer
Abstract Nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme in cellular redox
reactions, is closely associated with age-related functional degeneration and metabolic …

Lycopene supplementation to serum-free maturation medium improves in vitro bovine embryo development and quality and modulates embryonic transcriptomic …

S Sidi, OB Pascottini, D Angel-Velez… - Antioxidants, 2022 - mdpi.com
Bovine embryos are typically cultured at reduced oxygen tension to lower the impact of
oxidative stress on embryo development. However, oocyte in vitro maturation (IVM) is …