Role of plant alkaloids on human health: A review of biological activities

B Debnath, WS Singh, M Das, S Goswami… - Materials today …, 2018 - Elsevier
Alkaloids are plant secondary metabolite. They are well known nitrogen-containing natural
bioactive compounds. Cutting edge research is going on alkaloids to unravel novel …

Structure-bioactivity relationships of methylxanthines: Trying to make sense of all the promises and the drawbacks

JP Monteiro, MG Alves, PF Oliveira, BM Silva - Molecules, 2016 - mdpi.com
Methylxanthines are a group of phytochemicals derived from the purine base xanthine and
obtained from plant secondary metabolism. They are unobtrusively included in daily diet in …

Synthesis, experimental and computational study of a non-centrosymmetric material 3-methylbenzylammonium trioxonitrate

S Gatfaoui, N Issaoui, T Roisnel, H Marouani - Journal of Molecular …, 2021 - Elsevier
This paper shall address the synthesis and characterization of the novel non-
centrosymmetric inorganic-organic hybrid material 3-methylbenzylammonium nitrate with …

Experimental, computational, and in silico analysis of (C8H14N2) 2 [CdCl6] compound

I Jomaa, O Noureddine, S Gatfaoui, N Issaoui… - Journal of Molecular …, 2020 - Elsevier
The crystal structure of a novel compound (C 8 H 14 N 2) 2 [CdCl 6] denoted (MXDCdCl 6) is
discussed based on single crystal X-ray diffraction. This compound crystallizes in the triclinic …

Pharmacological potential of methylxanthines: Retrospective analysis and future expectations

J Monteiro, MG Alves, PF Oliveira… - Critical reviews in food …, 2019 - Taylor & Francis
Methylated xanthines (methylxanthines) are available from a significant number of different
botanical species. They are ordinarily included in daily diet, in many extremely common …

Deciphering non-covalent interactions of 1, 3-Benzenedimethanaminium bis (trioxonitrate): Synthesis, empirical and computational study

S Gatfaoui, N Issaoui, SA Brandán, M Medimagh… - Journal of Molecular …, 2022 - Elsevier
Benzenedimethanaminium bis (trioxonitrate), denoted by BD (NO 3) 2 was prepared and its
structure determined by X-ray crystallography. This compound solidifies into the triclinic …

Anti-obesity potential of natural methylxanthines

DF Carrageta, TR Dias, MG Alves, PF Oliveira… - Journal of Functional …, 2018 - Elsevier
Obesity is one of the most challenging health issue worldwide that has been steadily
increasing in the last decades. Obesity arises from a positive energy balance in result of …

Synthesis, structural and spectroscopic features, and investigation of bioactive nature of a novel organic-inorganic hybrid material 1H-1, 2, 4-triazole-4-ium …

S Gatfaoui, N Issaoui, A Mezni, F Bardak… - Journal of Molecular …, 2017 - Elsevier
The novel inorganic-organic hybrid material 1H-1, 2, 4-triazole-4-ium trioxonitrate (TAN)
have been elaborated and crystallized to the monoclinic system with space group P2 1/c …

Azafluorene derivatives as inhibitors of SARS CoV-2 RdRp: synthesis, physicochemical, quantum chemical, modeling and molecular docking analysis

M Venkateshan, M Muthu, J Suresh… - Journal of molecular …, 2020 - Elsevier
Abstract The crystal structures of 2-(1H-indol-3-yl)-4-phenyl-5H-indeno [(Cheng et al., 2007;
Lee et al., 2003) 1, 21, 2-b] pyridine-3-carbonitrile (Ia) and 2-(1H-indol-3-yl)-4-(4 …

Neuroprotective Effects of Theobromine in permanent bilateral common carotid artery occlusion rat model of cerebral hypoperfusion

JA Bhat, M Kumar - Metabolic Brain Disease, 2022 - Springer
Cerebral hypoperfusion (CH) is a common underlying mechanism of dementia disorders
linked to aberrations in the neurovascular unit. Hemodynamic disturbances adversely affect …