[HTML][HTML] Relaxin elicits renoprotective actions accompanied by increasing bile acid levels in streptozotocin-induced diabetic mice
Background The peptide hormone relaxin has potent anti-fibrotic and anti-inflammatory
properties in various organs, including the kidneys. However, the protective effects of relaxin …
properties in various organs, including the kidneys. However, the protective effects of relaxin …
Therapeutic potential of relaxin or relaxin mimetics in managing cardiovascular complications of diabetes
AG Devasia, M Shanmugham, A Ramasamy… - Biochemical …, 2024 - Elsevier
Diabetes mellitus is a metabolic disease with an escalating global prevalence. Despite the
abundance and relative efficacies of current therapeutic approaches, they primarily focus on …
abundance and relative efficacies of current therapeutic approaches, they primarily focus on …
Integrated metabolomics and phosphoproteomics reveal the protective role of exosomes from human umbilical cord mesenchymal stem cells in naturally aging mouse …
M Ling, C Tang, X Yang, N Yu, Y Song, W Ding… - Experimental Cell …, 2023 - Elsevier
Background Aging is characterized by a general decline in cellular function, which ultimately
affects whole body homeostasis. This study aimed to investigate the effects and underlying …
affects whole body homeostasis. This study aimed to investigate the effects and underlying …
Relaxin-2 plasma levels in atrial fibrillation are linked to inflammation and oxidative stress markers
A Aragón-Herrera, M Couselo-Seijas… - Scientific reports, 2022 - nature.com
Relaxin-2 exerts many favourable cardiovascular effects in pathological circumstances such
as atrial fibrillation (AF) and heart failure, but the mechanisms underlying its actions are not …
as atrial fibrillation (AF) and heart failure, but the mechanisms underlying its actions are not …
Characterization of feed efficiency-related key signatures molecular in different cattle breeds
C Yang, Z Huang, C Pan, S Wang - Plos one, 2023 - journals.plos.org
Feed efficiency is a major constraint in the beef industry and has a significant negative
correlation with residual feed intake (RFI). RFI is widely used as a measure of feed efficiency …
correlation with residual feed intake (RFI). RFI is widely used as a measure of feed efficiency …
Human recombinant relaxin-2 (serelaxin) regulates the proteome, lipidome, lipid metabolism and inflammatory profile of rat visceral adipose tissue
A Aragón-Herrera, S Feijóo-Bandín… - Biochemical …, 2024 - Elsevier
Abstract Recombinant human relaxin-2 (serelaxin) has been widely proven as a novel drug
with myriad effects at different cardiovascular levels, which support its potential therapeutic …
with myriad effects at different cardiovascular levels, which support its potential therapeutic …
Significance of plasma relaxin-2 levels in patients with primary hypertension and type 2 diabetes mellitus
O Pankova, O Korzh - Wiener Medizinische Wochenschrift, 2024 - Springer
Background This study aimed to evaluate plasma relaxin‑2 (RLN-2) levels in patients with
arterial hypertension (AH) and their relationships with clinical and laboratory parameters …
arterial hypertension (AH) and their relationships with clinical and laboratory parameters …