[HTML][HTML] Biomarkers of nutrition for development—folate review

LB Bailey, PJ Stover, H McNulty, MF Fenech… - The Journal of …, 2015 - Elsevier
Abstract The Biomarkers of Nutrition for Development (BOND) project is designed to provide
evidence-based advice to anyone with an interest in the role of nutrition in health …

Micronuclei as biomarkers of DNA damage, aneuploidy, inducers of chromosomal hypermutation and as sources of pro-inflammatory DNA in humans

M Fenech, S Knasmueller, C Bolognesi… - … Research/Reviews in …, 2020 - Elsevier
Micronuclei (MNi) are among the most widely studied biomarkers of DNA damage and
chromosomal instability in humans. They originate from chromosome fragments or intact …

The in vitro micronucleus technique

M Fenech - … Research/Fundamental and Molecular Mechanisms of …, 2000 - Elsevier
The study of DNA damage at the chromosome level is an essential part of genetic toxicology
because chromosomal mutation is an important event in carcinogenesis. The micronucleus …

Cytokinesis-block micronucleus cytome assay

M Fenech - Nature protocols, 2007 - nature.com
The cytokinesis-block micronucleus cytome assay is a comprehensive system for measuring
DNA damage, cytostasis and cytotoxicity. DNA damage events are scored specifically in …

HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures

M Fenech, WP Chang, M Kirsch-Volders… - … /Genetic Toxicology and …, 2003 - Elsevier
Criteria for scoring micronuclei and nucleoplasmic bridges in binucleated cells in the
cytokinesis-block micronucleus assay for isolated human lymphocyte cultures are described …

An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans

S Bonassi, A Znaor, M Ceppi, C Lando… - …, 2007 - academic.oup.com
The frequency of micronuclei (MN) in peripheral blood lymphocytes (PBL) is extensively
used as a biomarker of chromosomal damage and genome stability in human populations …

The HUman MicroNucleus project on eXfoLiated buccal cells (HUMNXL): The role of life-style, host factors, occupational exposures, health status, and assay protocol

S Bonassi, E Coskun, M Ceppi, C Lando… - … Research/Reviews in …, 2011 - Elsevier
The human buccal micronucleus cytome assay (BMCyt) is one of the most widely used
techniques to measure genetic damage in human population studies. Reducing protocol …

The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps

N Holland, C Bolognesi, M Kirsch-Volders… - … Research/Reviews in …, 2008 - Elsevier
The micronucleus (MN) assay in exfoliated buccal cells is a useful and minimally invasive
method for monitoring genetic damage in humans. This overview has concluded that …

The effect of age, gender, diet and lifestyle on DNA damage measured using micronucleus frequency in human peripheral blood lymphocytes

M Fenech, S Bonassi - Mutagenesis, 2011 - academic.oup.com
Micronucleus (MN) frequency in cytokinesis-blocked peripheral blood lymphocytes (PBL)
has become one of the best-established biomarkers for studying DNA damage occurring in …

Chromosomal changes: induction, detection methods and applicability in human biomonitoring

R Mateuca, N Lombaert, PV Aka, I Decordier… - Biochimie, 2006 - Elsevier
The objective of this state of the art paper is to review the mechanisms of induction, the fate,
the methodology, the sensitivity/specificity and predictivity of two major cytogenetic …