[PDF][PDF] A comprehensive review on eryptosis

E Pretorius, JN du Plooy, J Bester - Cellular Physiology and …, 2016 - karger.com
Erythrocytes (RBCs) are extremely sensitive cells, and although they do not have nuclei and
mitochondria, are important health indicators. This is particularly true because, during …

α-Lactalbumin, amazing calcium-binding protein

EA Permyakov - Biomolecules, 2020 - mdpi.com
α-Lactalbumin (α-LA) is a small (Mr 14,200), acidic (pI 4–5), Ca2+-binding protein. α-LA is a
regulatory component of lactose synthase enzyme system functioning in the lactating …

Casein kinase 1α mediates eryptosis: a review

A Tkachenko, A Onishchenko - Apoptosis, 2023 - Springer
Eryptosis is a coordinated non-lytic cell death of erythrocytes characterized by cell
shrinkage, cell membrane scrambling, Ca2+ influx, ceramide accumulation, oxidative stress …

Apoptosis and eryptosis: similarities and differences

A Tkachenko - Apoptosis, 2024 - Springer
Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …

Suicidal death of erythrocytes in cancer and its chemotherapy: A potential target in the treatment of tumor‐associated anemia

E Lang, R Bissinger, SM Qadri… - International Journal of …, 2017 - Wiley Online Library
In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis characterized by
cell shrinkage and cell membrane scrambling. Eryptotic erythrocytes are rapidly cleared …

Eryptosis-the neglected cause of anemia in end stage renal disease

F Lang, R Bissinger, M Abed, F Artunc - Kidney and Blood Pressure …, 2017 - karger.com
End stage renal disease (ESRD) invariably leads to anemia which has been mainly
attributed to compromised release of erythropoietin from the defective kidneys with …

[HTML][HTML] Nocodazole induced suicidal death of human erythrocytes

E Signoretto, S Honisch, M Briglia, C Faggio… - Cellular Physiology and …, 2016 - karger.com
Background: The microtubule assembly inhibitor nocodazole has been shown to trigger
caspase-independent mitotic death and caspase dependent apoptosis. Similar to apoptosis …

Structure and potential cellular targets of HAMLET-like anti-cancer compounds made from milk components

EM Rath, AP Duff, AP Håkansson… - … of Pharmacy & …, 2015 - journals.library.ualberta.ca
The HAMLET family of compounds (Human Alpha-lactalbumin Made Lethal to Tumours)
was discovered during studies on the properties of human milk, and is a class of protein-lipid …

Internalization properties of the anti-tumor α-lactalbumin-oleic acid complex

B Fang, M Zhang, H Wu, X Fan, F Ren - International journal of biological …, 2017 - Elsevier
Abstract α-Lactalbumin (α-LA) can bind oleic acid (OA) to form the anti-tumor α-LA-OA
complex. Previous studies suggested α-LA-OA induced apoptosis or autophagy in an …

Structures and mechanisms of formation of liprotides

JN Pedersen, HKS Frislev, JS Pedersen… - Biochimica et Biophysica …, 2020 - Elsevier
Many proteins form complexes called liprotides with oleic acid and other cis-fatty acids
under conditions where the protein is partially unfolded. The complexes vary in structure …