Advanced glycation end-products (AGEs): Formation, chemistry, classification, receptors, and diseases related to AGEs

A Twarda-Clapa, A Olczak, AM Białkowska… - Cells, 2022 - mdpi.com
Advanced glycation end-products (AGEs) constitute a non-homogenous, chemically diverse
group of compounds formed either exogeneously or endogeneously on the course of …

3D cell culture systems: tumor application, advantages, and disadvantages

O Habanjar, M Diab-Assaf, F Caldefie-Chezet… - International journal of …, 2021 - mdpi.com
The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …

Role of extracellular matrix in development and cancer progression

C Walker, E Mojares, A del Río Hernández - International journal of …, 2018 - mdpi.com
The immense diversity of extracellular matrix (ECM) proteins confers distinct biochemical
and biophysical properties that influence cell phenotype. The ECM is highly dynamic as it is …

Blood groups in infection and host susceptibility

L Cooling - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Blood group antigens represent polymorphic traits inherited among individuals and
populations. At present, there are 34 recognized human blood groups and hundreds of …

Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance

G Enkavi, M Javanainen, W Kulig, T Róg… - Chemical …, 2019 - ACS Publications
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

CD44-targeted nanocarrier for cancer therapy

P Kesharwani, R Chadar, A Sheikh, WY Rizg… - Frontiers in …, 2022 - frontiersin.org
Cluster of differentiation 44 (CD44) is a cell surface glycoprotein overexpressed in varieties
of solid tumors including pancreatic, breast, ovary, brain, and lung cancers. It is a multi …

Extracellular vesicle–matrix interactions

K Debnath, K Las Heras, A Rivera, S Lenzini… - Nature Reviews …, 2023 - nature.com
The extracellular matrix (ECM) harbours various signals to control cellular functions and the
materiality of tissues. Most efforts to synthetically reconstitute the matrix by biomaterial …

TSG-6: A multifunctional protein with anti-inflammatory and tissue-protective properties

AJ Day, CM Milner - Matrix Biology, 2019 - Elsevier
Tumor necrosis factor-(TNF) stimulated gene-6 (TSG-6) is an inflammation-associated
secreted protein that has been implicated as having important and diverse tissue protective …

Hyaluronan, a crucial regulator of inflammation

AC Petrey, CA de la Motte - Frontiers in immunology, 2014 - frontiersin.org
Hyaluronan (HA), a major component of the extracellular matrix (ECM), plays a key role in
regulating inflammation. Inflammation is associated with accumulation and turnover of HA …

Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications

CE Schanté, G Zuber, C Herlin, TF Vandamme - Carbohydrate polymers, 2011 - Elsevier
Hyaluronic acid (HA) is widely used for numerous medical applications, such as
viscosupplementation, eye surgery and drug delivery. A broad range of HA-based materials …