Overcoming skin barriers through advanced transdermal drug delivery approaches

V Phatale, KK Vaiphei, S Jha, D Patil, M Agrawal… - Journal of controlled …, 2022 - Elsevier
Upon exhaustive research, the transdermal drug delivery system (TDDS) has appeared as a
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …

Recent advances in transdermal drug delivery systems: A review

WY Jeong, M Kwon, HE Choi, KS Kim - Biomaterials research, 2021 - spj.science.org
Various non-invasive administrations have recently emerged as an alternative to
conventional needle injections. A transdermal drug delivery system (TDDS) represents the …

Where should siRNAs go: applicable organs for siRNA drugs

I Ahn, CS Kang, J Han - Experimental & Molecular Medicine, 2023 - nature.com
RNA interference mediated by small interfering RNAs (siRNAs) has been exploited for the
development of therapeutics. siRNAs can be a powerful therapeutic tool because the …

Nanocarriers-mediated drug delivery systems for anticancer agents: an overview and perspectives

Z Edis, J Wang, MK Waqas, M Ijaz… - International journal of …, 2021 - Taylor & Francis
Nanotechnology has been actively integrated as drug carriers over the last few years to treat
various cancers. The main hurdle in the clinical management of cancer is the development …

Multifaceted design and emerging applications of tissue adhesives

Z Ma, G Bao, J Li - Advanced Materials, 2021 - Wiley Online Library
Tissue adhesives can form appreciable adhesion with tissues and have found clinical use in
a variety of medical settings such as wound closure, surgical sealants, regenerative …

Advances in antimicrobial microneedle patches for combating infections

R Jamaledin, CKY Yiu, EN Zare, LN Niu… - Advanced …, 2020 - Wiley Online Library
Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional
topical administration because of poor drug penetration across the stratum corneum. This …

The role of ionic liquids in the pharmaceutical field: An overview of relevant applications

SN Pedro, CS R. Freire, AJD Silvestre… - International journal of …, 2020 - mdpi.com
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to
solid-state pharmaceuticals demand for effective solutions. To overcome some of these …

Electrospun fibers as carriers for topical drug delivery and release in skin bandages and patches for atopic dermatitis treatment

ZJ Krysiak, U Stachewicz - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
The skin is a complex layer system and the most important barrier between the environment
and the organism. In this review, we describe some widespread skin problems, with a focus …

Beneath the skin: a review of current trends and future prospects of transdermal drug delivery systems

AZ Alkilani, J Nasereddin, R Hamed, S Nimrawi… - Pharmaceutics, 2022 - mdpi.com
The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms
but is as convenient and easy to use for the patient as oral solid dosage forms. In recent …

Wearable and implantable devices for drug delivery: Applications and challenges

A Kar, N Ahamad, M Dewani, L Awasthi, R Patil… - Biomaterials, 2022 - Elsevier
Poor adherence to drug dosing schedule is responsible for∼ 50% of hospitalization cases.
Most patients fail to adhere to a strict dosing schedule due to invasive drug administration …