[PDF][PDF] Stability indicating HPLC method for the simultaneous determination of dapagliflozin and saxagliptin in bulk and tablet dosage form

T Deepan, MD Dhanaraju - Current Issues in Pharmacy and Medical …, 2018 - sciendo.com
A simple, fast, and highly selective RP-HPLC method was developed for the determination
of Dapagliflozin (DAP) and Saxagliptin (SAX) in API and tablet dosage form. The separation …

A new strategy for the determination of the antidiabetics alogliptin, saxagliptin and vildagliptin using all-solid state potentiometric sensors

AR Derar, N Ahmed, EM Hussien - BMC chemistry, 2023 - Springer
Herein, we report on the development of disposable screen printed carbon, nanostructure
thin film Au/Pt and Pt/Pt all-solid state potentiometric sensors for some antidiabetic …

Different approaches for the assessment of greenness of spectrophotometric methodologies utilized for resolving the spectral overlap of newly approved binary …

MG Fawzy, WE Hassan, AA Mostafa… - Spectrochimica Acta Part A …, 2022 - Elsevier
Simultaneous measurement of saxagliptin hydrochloride (SAG) and dapagliflozin
propanediol monohydrate (DAG) in bulk powder, laboratory-prepared mixtures, and …

Physiologically based pharmacokinetic (PBPK) modeling to predict CYP3A-mediated drug interaction between saxagliptin and nicardipine: bridging rat-to-human …

JM Lee, JH Yoon, HJ Maeng, YC Kim - Pharmaceutics, 2024 - mdpi.com
The aim of this study was to predict the cytochrome P450 3A (CYP3A)-mediated drug–drug
interactions (DDIs) between saxagliptin and nicardipine using a physiologically based …

[HTML][HTML] Simultaneous estimation of saxagliptin and dapagliflozin in human plasma by validated high performance liquid chromatography-ultraviolet method

S Donepudi, S Achanta - Turkish Journal of Pharmaceutical …, 2019 - ncbi.nlm.nih.gov
Objectives: The fixed dose combination of saxagliptin and dapagliflozin is a recently
approved antidiabetic medication. It is marketed under the brand name Qtern. The aim of …

LC–MS/MS analysis of metformin, saxagliptin and 5‐hydroxy saxagliptin in human plasma and its pharmacokinetic study with a fixed‐dose formulation in healthy …

PA Shah, JV Shah, M Sanyal… - Biomedical …, 2017 - Wiley Online Library
A specific and rapid liquid chromatography–tandem mass spectrometry method is proposed
for the simultaneous determination of metformin (MET), saxagliptin (SAXA) and its active …

A concise review of the bioanalytical methods for the quantitation of sitagliptin, an important dipeptidyl peptidase‐4 (DPP4) inhibitor, utilized for the characterization of …

PS Suresh, NR Srinivas… - Biomedical …, 2016 - Wiley Online Library
Inhibition of dipeptidyl peptidase‐4 (DPP4) is an emerging therapeutic approach for treating
type 2 diabetes and has revolutionized the concept of diabetes management. Sitagliptin is …

Design and application of molecularly imprinted electrochemical sensor for the new generation antidiabetic drug saxagliptin

NS Elmalahany, MAH Abdel‐Tawab, HM Elwy… - …, 2023 - Wiley Online Library
Saxagliptin (Saxa) belongs to a new generation of antidiabetic pharmaceutical compounds
used in combination with healthy diet and exercise to lower blood glucose levels in patients …

A Comprehensive and Critical Review on Analytical and Bioanalytical methods for Metformin Hydrochloride, Dapagliflozin, and Saxagliptin

S Desai, RB Maradia… - Current Pharmaceutical …, 2023 - ingentaconnect.com
A new antidiabetic drug combination of Metformin Hydrochloride, Dapagliflozin, and
Saxagliptin have been recently approved for type II diabetes. This is marketed by Takeda …

Quantitative determination of metformin, saxagliptin and 5-hydroxy saxagliptin simultaneously by hydrophilic interaction liquid chromatography-electrospray ionization …

Y Peng, Q Chang, N Yang, S Gu, Y Zhou, L Yin… - … of Chromatography B, 2018 - Elsevier
A simple, sensitive and specific hydrophilic interaction liquid chromatography coupled to
electrospray ionization mass spectrometric (HILIC–MS) method was developed and …