Status of major hemostatic components in the setting of COVID-19: the effect on endothelium, platelets, coagulation factors, fibrinolytic system, and complement

M Sayyadi, S Hassani, M Shams, A Dorgalaleh - Annals of Hematology, 2023 - Springer
The coagulation, fibrinolytic, anticoagulation, and complement systems are in delicate
balance with the vessel wall endothelium ensuring appropriate hemostasis. Coagulopathy …

Mechanisms of endothelial activation, hypercoagulation and thrombosis in COVID-19: a link with diabetes mellitus

I Valencia, J Lumpuy-Castillo, G Magalhaes… - Cardiovascular …, 2024 - Springer
Early since the onset of the COVID-19 pandemic, the medical and scientific community were
aware of extra respiratory actions of SARS-CoV-2 infection. Endothelitis, hypercoagulation …

Metabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation

FC Ceballos, A Virseda-Berdices, S Resino… - Frontiers in …, 2022 - frontiersin.org
Background metabolic changes through SARS-CoV-2 infection has been reported but not
fully comprehended. This metabolic dysregulation affects multiple organs during COVID-19 …

Coagulation biomarkers and coronavirus disease 2019 phenotyping: a prospective cohort study

E Corneo, R Garbelotto, G Prestes, CS Girardi… - Thrombosis …, 2023 - Springer
Background Because severe acute respiratory syndrome coronarivus 2 (SARS-CoV-2)
leads to severe conditions and thrombus formation, evaluation of the coagulation markers is …

Vascular risk factors for COVID-19 ARDS: endothelium, contact-kinin system

M Bailey, D Linden, H Guo-Parke, O Earley… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2 binds to ACE2 receptors, expressed within the lungs. Risk factors for
hospitalization include hypertension, diabetes, ischaemic heart disease and obesity …

[HTML][HTML] Targeting thromboinflammation in COVID-19–A narrative review of the potential of C1 inhibitor to prevent disease progression

P Urwyler, S Moser, M Trendelenburg, P Sendi… - Molecular …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is associated with
a clinical spectrum ranging from asymptomatic carriers to critically ill patients with …

The COMPASS-COVID-19-ICU study: Identification of factors to predict the risk of intubation and mortality in patients with severe COVID-19

GT Gerotziafas, P Van Dreden, DD Fraser, G Voiriot… - Hemato, 2022 - mdpi.com
In some patients, SARS-CoV-2 infection induces cytokine storm, hypercoagulability and
endothelial cell activation leading to worsening of COVID-19, intubation and death. Prompt …