Parkinson's disease (PD) is a neurodegenerative disease with a 200 year-long research
history. Our understanding about its clinical phenotype and pathogenesis remains limited …

Sex hormones and genes on the sex chromosomes are not only key factors in the regulation
of sexual differentiation and reproduction but they are also deeply involved in brain …

Neurodegenerative diseases, including Alzheimer disease (AD), Parkinson disease (PD),
multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and Huntington disease, are …

Although Parkinson disease (PD) is a progressive neurodegenerative disorder, available
animal models do not exhibit irreversible neurodegeneration, and this is a major obstacle in …

Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease. A greater prevalence and incidence of PD are reported in men than in …

Parkinson's disease (PD) is often most recognized for motor symptoms but associated non-
motor symptoms such as sexual dysfunction can significantly impact quality of life. This …

Body weight (BW) loss and reduced body mass index (BMI) are the most common peripheral
alterations in Huntington disease (HD) and have been found in HD mutation carriers and HD …

Accumulating epidemiological and clinical studies support a greater prevalence and
incidence of Parkinson's disease (PD) in men than women, suggesting a potential …

The greater prevalence and incidence of Parkinson's disease (PD) in men suggest a
beneficial effect of sex hormones. Neuroactive steroids have neuroprotective activities thus …

Parkinson's disease (PD) is well known for motor deficits such as bradykinesia. However,
patients often experience additional deficits in working memory, behavioral selection …