Molecular biology of osteosarcoma
AM Czarnecka, K Synoradzki, W Firlej, E Bartnik… - Cancers, 2020 - mdpi.com
Osteosarcoma (OS) is the most frequent primary bone cancer in children and adolescents
and the third most frequent in adults. Many inherited germline mutations are responsible for …
and the third most frequent in adults. Many inherited germline mutations are responsible for …
Molecular mechanism of ferroptosis in orthopedic diseases
L Gao, W Hua, L Tian, X Zhou, D Wang, Y Yang, G Ni - Cells, 2022 - mdpi.com
Ferroptosis is a new iron-dependent programmed cell death process that is directly
mediated by the accumulation of lipid peroxides and reactive oxygen species. Numerous …
mediated by the accumulation of lipid peroxides and reactive oxygen species. Numerous …
[HTML][HTML] lncRNA SNHG10 promotes the proliferation and invasion of osteosarcoma via wnt/β-catenin signaling
S Zhu, Y Liu, X Wang, J Wang, G Xi - Molecular Therapy-Nucleic Acids, 2020 - cell.com
Uncontrolled growth and an enforced epithelial-mesenchymal transition (EMT) process
contribute to the poor survival rate of patients with osteosarcoma (OS). Long noncoding …
contribute to the poor survival rate of patients with osteosarcoma (OS). Long noncoding …
[HTML][HTML] Targeting ferroptosis in osteosarcoma
J Zhao, Y Zhao, X Ma, B Zhang, H Feng - Journal of bone oncology, 2021 - Elsevier
Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents,
with high degree of malignancy and an extremely poor prognosis. Ferroptosis, a non …
with high degree of malignancy and an extremely poor prognosis. Ferroptosis, a non …
[HTML][HTML] Circular RNA hsa-circ-0016347 promotes proliferation, invasion and metastasis of osteosarcoma cells
H Jin, X Jin, H Zhang, W Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are a novel class of non-coding RNA which have recently shown
huge capabilities in the regulation of gene expression at the post-transcriptional level …
huge capabilities in the regulation of gene expression at the post-transcriptional level …
MicroRNAs signatures, bioinformatics analysis of miRNAs, miRNA mimics and antagonists, and miRNA therapeutics in osteosarcoma
MicroRNAs (miRNAs) involved in key signaling pathways and aggressive phenotypes of
osteosarcoma (OS) was discussed, including PI3K/AKT/MTOR, MTOR AND RAF-1 …
osteosarcoma (OS) was discussed, including PI3K/AKT/MTOR, MTOR AND RAF-1 …
Targeting Wnt/β-catenin signaling by microRNAs as a therapeutic approach in chemoresistant osteosarcoma
Osteosarcoma (OS) is an adolescent and young adult malignancy that mostly occurs in long
bones. The treatment of OS is still a big challenge for clinicians due to increasing …
bones. The treatment of OS is still a big challenge for clinicians due to increasing …
Knockdown of the oncogene lncRNA NEAT1 restores the availability of miR-34c and improves the sensitivity to cisplatin in osteosarcoma
Y Hu, Q Yang, L Wang, S Wang, F Sun, D Xu… - Bioscience …, 2018 - portlandpress.com
Aberrant expressions of long non-coding RNAs (lncRNAs) are the culprits of carcinogenesis
via regulating the tumor suppressor or oncogene. LncRNA nuclear enriched abundant …
via regulating the tumor suppressor or oncogene. LncRNA nuclear enriched abundant …
MAFG-driven osteosarcoma cell progression is inhibited by a novel miRNA miR-4660
H Shan, L Zhu, C Yao, Z Zhang, Y Liu, Q Jiang… - … Therapy-Nucleic Acids, 2021 - cell.com
Osteosarcoma (OS) is the most common primary bone malignancy in the adolescent
population. MAFG (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G) …
population. MAFG (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G) …
Circular RNAs in osteosarcoma: An update of recent studies
L Zeng, L Liu, WJ Ni, F Xie… - … Journal of Oncology, 2023 - spandidos-publications.com
Osteosarcoma (OS) prevailing in children and adolescents mainly occurs at the metaphysis
of long bones. As it is associated with a high invasive and metastatic ability, resistance to …
of long bones. As it is associated with a high invasive and metastatic ability, resistance to …