White matter (WM) occupies a large volume of the human cerebrum and is mainly composed
of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are …

The observation that antagonists of the N-methyl-D-aspartate receptor (NMDAR), such as
phencyclidine (PCP) and ketamine, transiently induce symptoms of acute schizophrenia had …

Insulin-like growth factor (IGF) signaling greatly impacts the development and growth of the
central nervous system (CNS). IGF-I and IGF-II, two ligands of the IGF system, exert a wide …

The role of the cerebellum in schizophrenia has been highlighted by Andreasen's
hypothesis of “cognitive dysmetria,” which suggests a general dyscoordination of …

Recent neuroimaging and postmortem studies have reported abnormalities in white matter
of schizophrenic brains, suggesting the involvement of oligodendrocytes in the …

Despite hundreds of structural MRI studies documenting smaller brain volumes on average
in schizophrenia compared to controls, little attention has been paid to group differences in …

Depressive disorder is a very frequent and heterogeneous syndrome. Structural imaging
techniques offer a useful tool in the comprehension of neurobiological alterations that …

The objective of this study was to use a combined local descriptor, namely scale invariance
feature transform (SIFT), and a non linear support vector machine (SVM) technique to …

Objective To clarify the relationship between amygdala-hippocampal volume and cognitive
performance in schizophrenia and bipolar disorder. Background Abnormalities of the …

Accumulating evidence suggest a life-long impact of disease related mechanisms on brain
structure in schizophrenia which may be modified by antipsychotic treatment. The aim of the …