Effects of clinical medications on male fertility and prospects for stem cell therapy

P Mo, Z Zhao, X Ke, Y Fan, C Li - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
An increasing number of men require long-term drug therapy for various diseases. However,
the effects of long-term drug therapy on male fertility are often not well evaluated in clinical …

Paternal low-dose benzo (a) pyrene exposure in rats impairs sexual development and fertility of the paternal lineage in F2 generation: A transgenerational study

BC Jorge, J Stein, ACC Reis, JN Bueno… - Toxicology, 2023 - Elsevier
Abstract The field of Paternal Origins of Health and Disease (POHaD) is highly relevant but
remains under-explored. The F2 generation from males indirectly exposed (F1-via germ …

Lactational exposure to venlafaxine provokes late repercussions on reproductive parameters in male rat offspring

S da Silva Moreira, B de Matos Manoel… - Journal of Applied …, 2023 - Wiley Online Library
Exposure to selective serotonin reuptake inhibitors can affect hormone‐dependent
processes, such as the brain sexual differentiation. Because the use of these …

Effect of antidepressant drug (fluoxetine) on the testes of adult male albino rats and the possible protective role of omega-3

BL Mahmoud, ESA El-Roghy… - Menoufia Medical …, 2018 - menoufia-med-j.com
Objective The aim of this study was to evaluate the possible protective effect of omega-3 on
testicular tissue damage induced by antidepressant drug (fluoxetine), in adult male albino …

Effect of fluoxetine on the testes of adult albino rats and the possible protective role of curcumin

BF Elsedawi, Y Hussein, MA Sabry, JA Aziz - Anatomical Science …, 2021 - Springer
Fluoxetine (FLX) is extensively used for the treatment of a diversity of psychiatric disorders,
mainly depression. However, it can adversely affect male fertility. This study was done to …

Downregulation of Serotonergic System Components in an Experimentally Induced Cryptorchidism in Rabbits

F Jiménez-Trejo, C Arriaga-Canon, LA Herrera… - International Journal of …, 2024 - mdpi.com
Cryptorchidism (CO) or undescended testes is defined as the failure of one or both testes to
be positioned inside the scrotum. Typically, cryptorchidism is detected at birth or shortly …

[HTML][HTML] The effects of exposure to fluoxetine during lactation on testicular tissue and sperm parameters in mice offspring

M Karimipour, A Ahmadi, MZ Javanmard… - Veterinary Research …, 2020 - ncbi.nlm.nih.gov
Fluoxetine is a selective serotonin reuptake inhibitor is commonly prescribed to treat
maternal depression in pregnancy and lactation. This study aimed to investigate the effects …

[HTML][HTML] Detrimental effects of cerium oxide nanoparticles on testis, sperm parameters quality, and in vitro fertilization in mice: An experimental study

E Hosseinalipour, M Karimipour… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Background Cerium oxide nanoparticles (CeO 2 NPs) as an important nanomaterial have a
wide range of applications in many fields and human beings' exposure to this nanomaterial …

Is lactational sertraline exposure safe for maternal health and the reproductive/neurobehavioral development of the descendants? A study in rats

AFQ Lozano, MS Moura, TRB Dinhani… - Reproductive …, 2023 - Elsevier
Although sertraline is considered one of the safest antidepressants in the lactation period,
there are still few studies that assess its impact on child development. Therefore, this …

Maternal exposure to fluoxetine during gestation and lactation does not alter plasma concentrations of testosterone, oestrogen or corticosterone in peripubertal …

MA Barbosa, LF Veríssimo, DCC Gerardin… - Reproduction …, 2019 - CSIRO Publishing
Antidepressants are widely used around the world, primarily for the treatment of mood
disorders, anxiety and pain syndromes. Women who use antidepressants often continue to …