Cellular activation pathways and interaction networks in vascularized composite allotransplantation

L Knoedler, S Knoedler, AC Panayi, CAA Lee… - Frontiers in …, 2023 - frontiersin.org
Vascularized composite allotransplantation (VCA) is an evolving field of reconstructive
surgery that has revolutionized the treatment of patients with devastating injuries, including …

Composite tissue allotransplantation: opportunities and challenges

J Iske, Y Nian, R Maenosono, M Maurer… - Cellular & molecular …, 2019 - nature.com
Vascularized composite allotransplants (VCAs) have unique properties because of diverse
tissue components transplanted en mass as a single unit. In addition to surgery, this type of …

Current status of vascularized composite allotransplantation

CL Kaufman, N Bhutiani, A Ramirez… - The American …, 2019 - journals.sagepub.com
The field of vascularized composite allotransplantation (VCA) has moved from a highly
experimental procedure to, at least for some patients, one of the best treatment alternatives …

Challenges and opportunities in vascularized composite allotransplantation of joints: a systematic literature review

L Zhang, IA Hoyos, C Zubler, R Rieben… - Frontiers in …, 2023 - frontiersin.org
Background Joint allotransplantation (JA) within the field of vascularized composite
allotransplantation (VCA) holds great potential for functional and non-prosthetic …

Applied bioengineering in tissue reconstruction, replacement, and regeneration

JM Colazo, BC Evans, AF Farinas… - … Engineering Part B …, 2019 - liebertpub.com
To this day, tissue reconstruction and replacement to address extensive tissue defects due
to trauma, tumor resection, genetic and/or chronic diseases, or excessive debridement …

Optimization of ex vivo machine perfusion and transplantation of vascularized composite allografts

LC Burlage, AG Lellouch, CB Taveau… - Journal of Surgical …, 2022 - Elsevier
Background Machine perfusion is gaining interest as an efficient method of tissue
preservation of Vascularized Composite Allografts (VCA). The aim of this study was to …

[HTML][HTML] Prolonged cold ischemia time results in local and remote organ dysfunction in a murine model of vascularized composite transplantation

N Datta, SG Devaney, RW Busuttil, K Azari… - American Journal of …, 2017 - Elsevier
Vascularized composite allotransplantation (VCA) is a viable reconstructive option for
complex tissue defects. Although grafts with a large muscular component may be uniquely …

Novel immunological and clinical insights in vascularized composite allotransplantation

B Kollar, B Pomahac, LV Riella - Current opinion in organ …, 2019 - journals.lww.com
Novel immunological and clinical insights in vascularized co... : Current Opinion in Organ
Transplantation Novel immunological and clinical insights in vascularized composite …

Methods of ex vivo analysis of tissue status in vascularized composite allografts

C Ton, S Salehi, S Abasi, JR Aggas, R Liu… - Journal of translational …, 2023 - Springer
Vascularized composite allotransplantation can improve quality of life and restore
functionality. However, the complex tissue composition of vascularized composite allografts …

[HTML][HTML] The contribution of the donor vascularised hand and face allograft in transplant rejection: An immunological perspective

KR Amin, JE Fildes - Transplant immunology, 2024 - Elsevier
Overcoming immunological rejection remains a barrier to the safe adoption of Vascularised
Composite Allotransplantation (VCA). To mitigate this risk, clinical protocols have been …