Critical assessment of the chemical space covered by LC–HRMS non-targeted analysis
T Hulleman, V Turkina, JW O'Brien… - Environmental …, 2023 - ACS Publications
Non-targeted analysis (NTA) has emerged as a valuable approach for the comprehensive
monitoring of chemicals of emerging concern (CECs) in the exposome. The NTA approach …
monitoring of chemicals of emerging concern (CECs) in the exposome. The NTA approach …
[HTML][HTML] Quantitative non-targeted analysis: bridging the gap between contaminant discovery and risk characterization
Chemical risk assessments follow a long-standing paradigm that integrates hazard, dose–
response, and exposure information to facilitate quantitative risk characterization. Targeted …
response, and exposure information to facilitate quantitative risk characterization. Targeted …
Transition to sustainable chemistry through digitalization
P Fantke, C Cinquemani, P Yaseneva, J De Mello… - Chem, 2021 - cell.com
Modern chemistry is the backbone of our society, but it is also a major contributor to global
environmental pollution and the ongoing climate crisis. The transition toward a sustainable …
environmental pollution and the ongoing climate crisis. The transition toward a sustainable …
Suspect screening, prioritization, and confirmation of environmental chemicals in maternal-newborn pairs from San Francisco
Our proof-of-concept study develops a suspect screening workflow to identify and prioritize
potentially ubiquitous chemical exposures in matched maternal/cord blood samples, a …
potentially ubiquitous chemical exposures in matched maternal/cord blood samples, a …
Potential for machine learning to address data gaps in human toxicity and ecotoxicity characterization
K von Borries, H Holmquist, M Kosnik… - Environmental …, 2023 - ACS Publications
Machine Learning (ML) is increasingly applied to fill data gaps in assessments to quantify
impacts associated with chemical emissions and chemicals in products. However, the …
impacts associated with chemical emissions and chemicals in products. However, the …
Towards neuroecosociality: mental health in adversity
Social theory has much to gain from taking up the challenges of conceptualizing 'mental
health'. Such an approach to the stunting of human mental life in conditions of adversity …
health'. Such an approach to the stunting of human mental life in conditions of adversity …
The chemical landscape of high-throughput new approach methodologies for exposure
The rapid characterization of risk to humans and ecosystems from exogenous chemicals
requires information on both hazard and exposure. The US Environmental Protection …
requires information on both hazard and exposure. The US Environmental Protection …
New approach methods to evaluate health risks of air pollutants: Critical design considerations for in vitro exposure testing
Air pollution consists of highly variable and complex mixtures recognized as major
contributors to morbidity and mortality worldwide. The vast number of chemicals, coupled …
contributors to morbidity and mortality worldwide. The vast number of chemicals, coupled …
[HTML][HTML] Cutting-edge computational chemical exposure research at the US Environmental Protection Agency
Exposure science is evolving from its traditional “after the fact” and “one chemical at a time”
approach to forecasting chemical exposures rapidly enough to keep pace with the …
approach to forecasting chemical exposures rapidly enough to keep pace with the …
HExpPredict: In Vivo Exposure Prediction of Human Blood Exposome Using a Random Forest Model and Its Application in Chemical Risk Prioritization
Background: Due to many substances in the human exposome, there is a dearth of
exposure and toxicity information available to assess potential health risks. Quantification of …
exposure and toxicity information available to assess potential health risks. Quantification of …